Pregnancy induces complex changes concerned with hemostasis. Normal pregnancy is associated with hypercoagulable state which becomes more pronounced at term while in pre-eclampsia or pregnancyinduced hypertension (PIH), localized coagulation fibrinolytic imbalance has been reported(l,2). Various coagulation factors are decreased in concentration in PIH, especially fibrinogen, factor V, VII, VII...

BACKGROUND Bleeding complications in cardiac surgery may lead to increased morbidity and mortality. Traditional blood coagulation tests are not always suitable to detect rapid changes in the patient's coagulation status. Point-of-care instruments such as the TEG (thromboelastograph) and RoTEM (thromboelastometer) have been shown to be useful as a guide for the clinician in the choice of blood p...

Sepsis almost invariably leads to hemostatic abnormalities, ranging from insignificant laboratory changes to severe disseminated intravascular coagulation. There is compelling evidence from clinical and experimental studies that disseminated intravascular coagulation is involved in the pathogenesis of microvascular dysfunction and contributes to organ failure. Data from the PROWESS phase III cl...

BACKGROUND Intraoperative cardiovascular deterioration as a result of pulmonary embolization of bone marrow fat is a potentially serious complication during vertebroplasty. The release of fatty material and thromboplastin from the bone marrow cavity during vertebroplasty may activate the coagulation cascade resulting in thrombogenesis, and pharmacological prophylaxis may therefore prevent cardi...

BACKGROUND Hemorrhagic shock contributes to coagulopathy after trauma. We investigated daily changes of coagulation components and coagulation function for 5 days in hemorrhaged and resuscitated pigs. METHODS Fourteen pigs were randomized into the sham control (C) and the hemorrhage and lactated Ringer's resuscitation (H-LR) groups. On day 1, hemorrhage was induced in the H-LR group by bleedi...

1009 April 2014 C ARDIAC arrest occurs with an estimated annual incidence of 92 to 189 cases per 100,000 individuals and carries a poor prognosis despite advances in modern medicine.1 Even for patients in whom spontaneous circulation is restored, their subsequent hospital course is fraught with potential complications. Derangements in the coagulation and fibrinolytic systems frequently occur as...

PURPOSE Although coagulation activation has been reported in chronic urticaria, data pertaining to detailed changes in coagulation factors and global coagulation status are lacking. The current study evaluated global coagulation status in patients with chronic urticaria using thrombin generation assay (TGA) and the levels of individual coagulation factors. METHODS Patients with chronic urtica...

OBJECTIVES To review the effects of exercise on haemostasis and examine the possible clinical sequelae of these changes. METHODS The search strategy included articles from 1966 to August 2002 using Medline and SportDiscus databases, and cross referencing the bibliographies of relevant papers. RESULTS Exercise results in activation of both the coagulation and fibrinolytic cascades, as shown ...

in this study, different methods of separating of the microalgae from the culture medium as one of the most important and expensive steps in achieving commercial production of biodiesel from microalgae was investigated. electro coagulation-flotation (ecf) was preferred among these methods due to its process simplicity and capability to scale up. the effect of three parameters, i.e., initial ph,...