Carbon monoxide (CO) poisoning causes brain damage, which is attenuated by treatment with hydrogen [1], [2], a scavenger selective to hydroxyl radical (•OH) [3]. This suggests a role of •OH in brain damage due to CO poisoning. Studies have shown strong enhancement of •OH production in rat striatum by severe CO poisoning with a blood carboxyhemoglobin (COHb) level > 70% due to 3000 ppm CO, but n...

The purpose of this review is to examine the literature regarding occult and chronic exposure to low levels of carbon monoxide (CO)— that is, levels insufficient to cause emergency department attendance or admission to hospital with a clinical diagnosis of acute CO poisoning, although this in fact is the cause of the symptoms. More is known about acute CO poisoning, but knowledge and awareness ...

Dear Editor, Carbon monoxide (CO) poisoning is a leading cause of death by suicide.1 Acute CO intoxication may induce hypoxic encephalopathy with variable presentations, ranging from confusion to deep coma but most recover completely from the acute episode following CO poisoning. However, up to 30% of survivors develop neuropsychiatric and cognitive manifestations 1 week to 6 months after CO ex...

Background: Carbon monoxide (CO) poisoning has remained a common, serious and often unrecognized event and constitutes a public health problem in Morocco. The objective of this study is to describe the epidemiological and clinical profile and risk factors of CO poisoning in the region of Fez-Boulemane, Morocco. Methods: This is a retrospective study on CO poisoning cases occurred in the region ...

Over the past 15 years, a number of epidemics of carbon monoxide (CO) poisoning related to various storms have been reported. While the geographical location of these outbreaks and the types of storms involved has been diverse, review of the events reveals a number of common factors and themes. This paper summarizes the details of 9 published reports describing CO poisoning associated with 11 d...

Carbon monoxide (CO) is a well-known chemical asphyxiant, which causes tissue hypoxia with prominent neurological and cardiovascular injury. After exposure to CO, several cardiac manifestations have been reported, including arrhythmias, acute myocardial infarction, and pulmonary edema. However, an ST elevation myocardial infarction (STEMI) due to CO poisoning is a very rare presentation, and th...

BACKGROUND This report describes carbon monoxide (CO) poisoning in two workers using a hired forklift truck within a coldstore. The diagnosis was not considered until day 6 of the incident, and so measurements of blood or breath CO at the time of acute illness were unavailable. AIMS To determine whether CO poisoning may be diagnosed retrospectively, where blood or breath CO measurements are u...

BACKGROUND Highway vehicle CO emissions have decreased 85% since introduction of the catalytic converter in 1975. We sought to examine whether morbidity and mortality from intentional motor vehicle-related CO poisoning have also changed. METHODS Vehicle CO emissions data from 1970-2013 were obtained from the U.S. Environmental Protection Agency. U.S. Centers for Disease Control and Prevention...

Since hyperbaric oxygen therapy (HBO2) appeared as a treatment for CO poisoning in 1960, whether and when to use it for CO poisoning have often been debated. HBO2 has been advocated to treat severe CO poisoning to limit delayed and permanent neurologic sequelae. Initially, inferences about efficacy were based on clinical experience and uncontrolled studies, but since1989, six prospective clinic...