Glutaric aciduria type 1 (glutaryl-CoA dehydrogenase deficiency, glutaric acidemia 1) (OMIM 231670) is an autosomal recessive disease caused by mutations in the gene encoding enzyme glutaryl-CoA (GCDH). Glutaryl-CoA (GCDH) plays important role degradation metabolism of L-lysine, L-hydroxylysine and L-tryptophan. The insufficiency or absence leads to accumulation by-products such amino acids as ...

In a prospective clinical trial, the incidence of scrotal tongue in psoriatic patients was studied. One hundred psoriatics and the same number of non-psoriatic individuals were evaluated for the incidence of fissured tongue, age, duration of illness, and clinical types of psoriasis. In this study 49 psoriatic patients (49%) and 28 non-psoriatic persons (28%) had fissured tongue. The most c...

most contemporary clinical reasoning tests typically assess non-automatic thinking. therefore, a test is needed to measure automatic reasoning or pattern recognition, which has been largely neglected in clinical reasoning tests. the puzzle test (pt) is dedicated to assess automatic clinical reasoning in routine situations. this test has been introduced first in 2009 by monajemi et al in the oly...

background: objective structured clinical examination (osce) is one of the best methods of evaluating the achievement of domains such as educational objectives and cognitive, emotional, and psycho-motor aspects of medical students. according to available evidences, no study has been conducted  on the evaluating of osce in midwifery students. the main purpose of this study was the evaluation of ...