OBJECTIVE Several clinical studies suggest that black cohosh may be effective in climacteric complaints. However, evidence of its efficacy based on current quality standards has been limited. METHODS This randomized, multicenter, double-blind clinical trial compared the efficacy and tolerability of the isopropanolic black cohosh extract in the treatment of climacteric complaints compared with...

OBJECTIVE to assess the therapeutic efficacy and safety of oral estriol for the treatment of climacteric symptoms in postmenopausal women. METHODS 68 postmenopausal women with climacteric symptoms received oral estriol, 2 mg/day, daily for 12 months. We evaluated the degree of climacteric complaints with estriol therapy; serum levels of gonadotropins, estradiol (E2) and lipids; biochemical ma...

It is shown that a sequential development of a serie-s of enzyme systems occurs in the peel of the apple as the respiration climacteric develops in the wvhole fruit. The sequence of development of these systems, i.e. acetate incorporation into lipid, production of ethylene, inoorporation of amino acid into protein and, finally, the decarboxylation of added malate (ma,late effect) is the same as...

\V;hether the toimato fruit is left to ripen on or off the plant, a marked increase in its respiratory rate knowni as the climacteric is observed as it passes from the mature green to the ripe stage (4, 7, 15, 19). A number of hypotheses have been advanced to exllain this climacteric rise in respiration (3, 10). It has been suggested that the climacteric rise is caused by increased utilization ...

The ripening of fruit is accompanied by a group of physiological and chemical changes whichl are characteristic and moderately uniform as between different species of plants. Typical coimiponents of the ripening process are pectic transformations which lead to fruit softening, changes in fruit color, often with the disappearance of pigment such as chlorophyll and the appearance of new secondary...

CONTEXT AND OBJECTIVE Climacteric symptoms may vary between different countries and cultures. Socioeconomic factors and climate may be implicated. The aim of this study was to identify climacteric symptomatology among very low-income Brazilian women, living in a hot and humid region. DESIGN AND SETTING This cross-sectional population-based study was conducted in Cuiabá, at Júlio Müller Univer...

once a year for vision ; when their vision falls below ??? they are no longer fit for duty; such patients remain under my observation of necessity. The first symptom the patient complains of, especially railway officials and sportsmen, is that their distant vision is failing, no complaint being made of their near vision. A man's vision will be reduced to T%or even before he complains severely o...