نتایج جستجو برای: ck17

تعداد نتایج: 66  

2017
Keisuke Kawashima Naoki Watanabe Sho Tawada Takahito Adachi Makoto Yamada Yusuke Kitoh Tamotsu Takeuchi Takuji Tanaka

Although intrabiliary metastasis of carcinoma in the liver is unusual, intraductal and/or intraepithelial spread of cancer cells along intrahepatic bile ducts is now well recognized as hepatic metastasis. However, several clinical and laboratory findings, including images, lead us to differentially diagnose from primary intrahepatic cholangiocarcinoma. We report here on a case of colonic adenoc...

2014
Hong Ji Ning Ai Qinghuai Li Kaili Zhang Wang Di

OBJECTIVE To explore the correlation between the clinical pathologies of breast cancer in the elderly and youths as well as their prognosis. METHODS Two hundred and eighty breast cancer patients were divided into a youth group (<60, n=120) and an elderly group (≥60, n=160) according to the age. Their routine clinical pathological indices and immune indices were observed and determined, and th...

2014
Triantafyllia Koletsa Flora Stavridi Mattheos Bobos Ioannis Kostopoulos Vassiliki Kotoula Anastasia G Eleftheraki Irene Konstantopoulou Christos Papadimitriou Anna Batistatou Helen Gogas Angelos Koutras Dimosthenis V Skarlos George Pentheroudakis Ioannis Efstratiou Dimitrios Pectasides George Fountzilas

BACKGROUND alphaB-crystallin is a small heat shock protein that has recently been characterized as an oncoprotein correlating with the basal core phenotype and with negative prognostic factors in breast carcinomas. The purpose of this study was to evaluate alphaB-crystallin with respect to clinicopathological parameters and the outcome of patients with operable high-risk breast cancer. METHOD...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Emad A Rakha Somaia E Elsheikh Muhammed A Aleskandarany Hany O Habashi Andrew R Green Desmond G Powe Maysa E El-Sayed Ahmed Benhasouna Jean-Sébastien Brunet Lars A Akslen Andy J Evans Roger Blamey Jorge S Reis-Filho William D Foulkes Ian O Ellis

PURPOSE Triple-negative (TN; estrogen receptor, progesterone receptor, and HER-2 negative) cancer and basal-like breast cancer (BLBC) are associated with poor outcome and lack the benefit of targeted therapy. It is widely perceived that BLBC and TN tumors are synonymous and BLBC can be defined using a TN definition without the need for the expression of basal markers. EXPERIMENTAL DESIGN We h...

Journal: :Asian Pacific journal of cancer prevention : APJCP 2014
Tuenjai Chuangsuwanich Tawatchai Pongpruttipan Pornchai O-Charoenrat Chulaluk Komoltri Suwapee Watcharahirun Doonyapat Sa-Nguanraksa

BACKGROUND To correlate breast cancer subtypes with prognostic factors, microvessel density (MVD), vascular endothelial growth factor (VEGF) expression and clinical features. MATERIALS AND METHODS One hundred cases of primary breast carcinoma were classified using biomarkers on tissue microarray as: luminal A [estrogen receptor (ER) +, HER2-, Ki-67≤14%], luminal B [ER+, HER2+ or ER+, HER2-, K...

2011
Sibel Yenidunya Reyhan Bayrak Hacer Haltas

BACKGROUND/OBJECTIVE While several prognostic factors have been identified in breast carcinoma, the clinical outcome remains hard to predict for individual patients. Better predictive markers are needed to help guide difficult treatment decisions. Axillary lymph node metastasis (ALNM) is one of the most important prognostic determinants in breast carcinoma; however, the reasons why tumors vary ...

Journal: :Archives of dermatology 2005
Reuven Bergman Rinat Schein-Goldshmid Zeev Hochberg Ofer Ben-Izhak Eli Sprecher

OBJECTIVE To establish the unique and common clinical and microscopic characteristics of the alopecias associated with vitamin D-dependent rickets (VDDR) type IIA and with hairless gene mutations. DESIGN A comparative clinical, histologic, and immunohistochemical study of the alopecias in 6 patients with VDDR IIA and 4 patients with atrichia with papular lesions (APL) and/or alopecia universa...

2006
Cezar Stroescu Vlad Herlea Adrian Dragnea Irinel Popescu

Aim. To study the differences between the hepatocellular carcinoma (HCC) and peripheral type of cholangiocarcinoma (CHC) using cytokeratin (CK) and carcinoembryonic antigen (CEA) expressions and to assess their accuracy on paraffin sections in the differential diagnosis. Material and method. The following antibodies were analyzed: AB1 complex (anti CK9-CK20), AB2 complex (anti CK1-CK8), pCEA, a...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Torsten Stein Karen N Price Joanna S Morris Victoria J Heath Roderick K Ferrier Alexandra K Bell Marie-Anne Pringle René Villadsen Ole W Petersen Guido Sauter Gareth Bryson Elizabeth A Mallon Barry A Gusterson

PURPOSE Microarray studies have linked Annexin A8 RNA expression to a "basal cell-like" subset of breast cancers, including BRCA1-related cancers, that are characterized by cytokeratin 5 (CK5) and CK17 expression and show poor prognosis. We assessed Annexin A8's contribution to the overall prognosis and its expression in normal, benign, and cancerous tissue and addressed Annexin A8's physiologi...

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