BACKGROUND Renal dysfunction is one of the most common complications of cirrhosis with high morbidity and mortality. SUMMARY In subjects with cirrhosis, renal dysfunction can present either as a direct consequence of cirrhosis (e.g. hepatorenal syndrome type I and type II) or secondary to etiologies other than cirrhosis (chronic kidney disease due to diabetic nephropathy, prerenal azotemia), ...

Advanced oxidation protein products (AOPPs) are protein markers of oxidative stress with pro-inflammatory properties that accumulated in liver cirrhosis. In the present study, we investigated the association between chronic inflammatory response triggered by AOPPs and the severity of liver disease as assessed by the Child-Pugh score. Plasma concentrations of AOPPs and inflammatory markers such ...

Abstract Muscle cramps appearing in liver cirrhosis substantially affect the quality of life these patients. The prevalence painful muscle can be up to 88%. exact mechanism by which occur is unknown. management this symptom not easy because there no uniformly accepted recommendation about what kind supplementation or medicine (or both) used exactly. aim our study review treatment options for ci...

Background The rate of hospital admissions for cirrhosis increased 1.3-fold during 2008–2016 in Queensland. Alcohol misuse was a contributing factor 55% and 40% patients had at least one comorbidity. Aims To examine the temporal change aetiology liver disease presence comorbidity admitted with cirrhosis. Methods Population-based retrospective cohort study all people treated (10 254 patients) Qu...

background: to glean insights into the relationship among hepatitis b virus (hbv) genotype/subgenotypes, a1762t/g1764a mutations and advanced liver disease such as liver cirrhosis (lc) and hepatocellular carcinoma (hcc) in southeast china. methods: a case-control study was performed, consisting of chronic hepatitis b (chb) patients (n=160), lc patients (n=150), and hcc patients (n=156). fluores...

several studies have shown that hepatocyte membrane composition changes in patients with cholestasis and cirrhosis. these alterations that are because of intracellular oxidative stress are supposed to be reflected in erythrocyte membrane. the aim of this study was to investigate the modification of erythrocyte membrane along with hexokinase and antioxidant enzymes during development of cirrhosi...

Diabetes Mellitus is Associated With Higher Risk of Developing Decompensated Cirrhosis in Chronic Hepatitis C Patients. Saeed MJ1, Olsen MA, Powderly WG, Presti RM. J Clin Gastroenterol. 2017 Jan;51(1):70-76. GOALS: To investigate the association of diabetes with risk of decompensated cirrhosis in patients with chronic hepatitis C (CHC). BACKGROUND: Direct-acting antivirals are highly effective...

BACKGROUND Patients with liver cirrhosis are at increased risk of serious bacterial infections carrying a high case fatality rate. Case reports have suggested an association between liver cirrhosis and pyogenic liver abscess. AIMS To estimate the risk and case fatality rate of pyogenic liver abscess in Danish patients with liver cirrhosis compared with the background population. METHODS Ide...

Cirrhosis is one type of liver disease and caused by forming fibrosis so that changes the structure become abnormal. Based on presence ascites, varicose veins, bleeding, cirrhosis divided into four clinical stages. This study aims to find best classification model using support vector machine (SVM). SVM a supervised learning method hyperplane with maximum margin. In this study, resulted useful ...