نتایج جستجو برای: circadian type

تعداد نتایج: 1364492  

Journal: :The New phytologist 2014
Antony N Dodd Neil Dalchau Michael J Gardner Seong-Jin Baek Alex A R Webb

A circadian rhythm matched to the phase and period of the day-night cycle has measurable benefits for land plants. We assessed the contribution of circadian period to the phasing of cellular events with the light : dark cycle. We also investigated the plasticity of circadian period within the Arabidopsis circadian oscillator. We monitored the circadian oscillator in wild-type and circadian peri...

2012
Xiping Zhang Samir P. Patel John J. McCarthy Alexander G. Rabchevsky David J. Goldhamer Karyn A. Esser

The myogenic differentiation 1 (MyoD) gene is a master regulator of myogenesis. We previously reported that the expression of MyoD mRNA oscillates over 24 h in skeletal muscle and that the circadian clock transcription factors, BMAL1 (brain and muscle ARNT-like 1) and CLOCK (circadian locomotor output cycles kaput), were bound to the core enhancer (CE) of the MyoD gene in vivo. In this study, w...

Journal: :The Plant cell 2006
Patrice A Salomé Jennifer P C To Joseph J Kieber C Robertson McClung

Light and temperature are potent environmental signals used to synchronize the circadian oscillator with external time and photoperiod. Phytochrome and cryptochrome photoreceptors integrate light quantity and quality to modulate the pace and phase of the clock. PHYTOCHROME B (phyB) controls period length in red light as well as the phase of the clock in white light. phyB interacts with ARABIDOP...

Journal: :Pathologie-biologie 2007
X-M Li B Claustrat M-H Hastings U Albrecht F Lévi

The relation between circadian physiology (rest-activity and body temperature) and the growth of a grafted tumor (Glasgow osteosarcoma-GOS) was investigated in the mice with mutation of clock gene (ClockDelta19(-)) or gene controlled by the clock (Vpac(-/-)). Circadian rhythms in temperature and activity were stable, with an approximately 24-h period in all the mice synchronized by the alternat...

Journal: :Journal of bacteriology 2003
Mitsunori Katayama Takao Kondo Jin Xiong Susan S Golden

We generated random transposon insertion mutants to identify genes involved in light input pathways to the circadian clock of the cyanobacterium Synechococcus elongatus PCC 7942. Two mutants, AMC408-M1 and AMC408-M2, were isolated that responded to a 5-h dark pulse differently from the wild-type strain. The two mutants carried independent transposon insertions in an open reading frame here name...

2018
Panshak P. Dakup Kenneth I. Porter Alexander A. Little Rajendra P. Gajula Hui Zhang Elena Skornyakov Michael G. Kemp Hans P.A Van Dongen Shobhan Gaddameedhi

Cisplatin is one of the most commonly used chemotherapeutic drugs; however, toxicity and tumor resistance limit its use. Studies using murine models and human subjects have shown that the time of day of cisplatin treatment influences renal and blood toxicities. We hypothesized that the mechanisms responsible for these outcomes are driven by the circadian clock. We conducted experiments using wi...

Journal: :The Plant cell 2006
Peter D Gould James C W Locke Camille Larue Megan M Southern Seth J Davis Shigeru Hanano Richard Moyle Raechel Milich Joanna Putterill Andrew J Millar Anthony Hall

Circadian clocks maintain robust and accurate timing over a broad range of physiological temperatures, a characteristic termed temperature compensation. In Arabidopsis thaliana, ambient temperature affects the rhythmic accumulation of transcripts encoding the clock components TIMING OF CAB EXPRESSION1 (TOC1), GIGANTEA (GI), and the partially redundant genes CIRCADIAN CLOCK ASSOCIATED1 (CCA1) an...

2017
Judit Meyer-Kovac Isa Kolbe Lea Ehrhardt Alexei Leliavski Jana Husse Gabriela Salinas Thomas Lingner Anthony H. Tsang Johanna L. Barclay Henrik Oster

OBJECTIVE Circadian Clock gene mutant mice show dampened 24-h feeding rhythms and an increased sensitivity to high-fat diet (HFD) feeding. Restricting HFD access to the dark phase counteracts its obesogenic effect in wild-type mice. The extent to which altered feeding rhythms are causative for the obesogenic phenotype of Clock mutant mice, however, remains unknown. METHODS Metabolic parameter...

2010
W. John Sheward Erik Naylor Seymour Knowles-Barley J. Douglas Armstrong Gillian A. Brooker Jonathan R. Seckl Fred W. Turek Megan C. Holmes Phyllis C. Zee Anthony J. Harmar

BACKGROUND Diurnal variations in the incidence of events such as heart attack and stroke suggest a role for circadian rhythms in the etiology of cardiovascular disease. The aim of this study was to assess the influence of the suprachiasmatic nucleus (SCN) circadian clock on cardiovascular function. METHODOLOGY/PRINCIPAL FINDINGS Heart rate (HR), blood pressure (BP) and locomotor activity (LA)...

Journal: :The National medical journal of India 2015
Garima Shukla Bhavna Kaul Anupama Gupta Vinay Goyal Madhuri Behari

BACKGROUND Circadian rhythm sleep disorder-advanced sleep-phase type is a relatively uncommon disorder, mostly seen among the elderly population. Impaired circadian rhythms have been reported in neurodegenerative conditions; however, there are no reports of any circadian rhythm sleep disorder among patients with Parkinsonian syndromes. We report two patients who presented with this circadian rh...

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