Pain is the most common reason why patients see a physician. Within the USA, it has been estimated that at least 116 million US adults suffer from chronic pain, with an estimated annual national economic cost of $560-635 billion. While pain is in part a sensory process, like sight, touch, or smell, pain is also in part an emotional experience, like depression, anxiety, or anger. Thus, chronic p...

Spinal cord stimulation has been utilized for over 40 years and has been proven to provide therapeutically effective pain relief from chronic conditions like failed back surgery, regional pain syndromes and neuralgias. Several measurable outcomes in VAS pain scores, disability scores and quality of life scales have shown consistent improvement with SCS in patients with back pain and leg pain [1...

BACKGROUND Rating scales like the visual analogue scale, VAS, and the verbal rating scale, VRS, are often used for pain assessments both in clinical work and in research, despite the lack of a gold standard. Interchangeability of recorded pain intensity captured in the two scales has been discussed earlier, but not in conjunction with taking the influence of pain etiology into consideration. ...

The proliferation and differentiation of cerebellar granule cell precursors (GCPs) are highly regulated spatiotemporally during development. We focused on cyclic phosphatidic acid (cPA) as a lipid mediator with a cyclic phosphate group as a regulatory factor of GCPs. While its structure is similar to that of lysophosphatidic acid (LPA), its function is very unique. cPA is known to be present in...

aim and background: pain is a complex experience involving psychological factors which results in functional disorder. this study aimed to analyze the correlation between cognitive and emotional factors with chronic low back pain among women in isfahan, iran. methods and materials: in this cross-sectional research, the target population included all women with chronic low back pain that referre...

purpose: the purpose of this study is to evaluate the effect of acceptance and commitment therapy for children with chronic pain (chact) on the function of 7 to 12 year-old children. thus, the basic problem of the current study is whether chact can improve the function level of 7 to 12 year-old children with chronic pain? method: according to the criteria of chronic pain, a number of children w...

OBJECTIVE The aim of this study was to examine the associations between coping and adjustment to chronic pain in a sample of patients from Portugal and to discuss the findings with respect to published findings from two studies using patients from the United States. DESIGN Two brief measures of pain coping were translated and administered with measures of physical and psychological functionin...

background and objectives : temporomandibular disorder (tmd) refers to chronic pain of the temporomandibular joint (tmj) associated with headache, neck pain, shoulder pain or back pain. the origin of these pains may be related to tmd. many patients with chronic headache undergo different treatments for long periods of time with no cure. these headaches can be treated with proper diagnosis. this...

BACKGROUND This cross validation study examined the reliability of the Multidimensional Pain Inventory (MPI) and the stability of the Multidimensional Pain Inventory Classification System of the empirically derived subgroup classification obtained by cluster analysis in chronic musculoskeletal pain. Reliability of the German Multidimensional Pain Inventory was only examined once in the past in ...

background: chronic pain depends on many physical and  psychological factors. the aim of this study was  to determine the relationship between anxiety and chronic pain in adult referring to health centers in yazd, iran.  methods: this descriptive study conducted on 397 adults aged between 31 and 87years. the depression, anxiety, stress scale -21(dass-21) was used to measure depression, anxiety ...