weakness of two month’s duration. She had been diagnosed with anorexia nervosa (binge-eating/purging subtype) at the age of 21 years. She had a history of repeated admissions for hypokalemia caused by self-induced vomiting and abuse of laxatives. On examination, her body mass index was 14.3 kg/m2. Laboratory values showed a serum creatinine level of 51.3 (normal 18–106) μmol/L, a serum potassiu...

INTRODUCTION The elderly population is growing and aging in better clinical conditions than in the past. However, the distribution and course of kidney diseases in elderly patients are not well known partially due to reluctance to indicate renal biopsies in those patients. OBJECTIVE To evaluate the distribution, clinical features, and outcomes of nephropathies diagnosed by biopsy in the elder...

An association between non-opioid analgesic agents and chronic kidney disease has long been suspected. The presumed development of chronic renal impairment following protracted excessive use of non-opioid analgesia is known as analgesic nephropathy. Many accept analgesic nephropathy as a real entity despite a paucity of robust scientific evidence. The weight of available observational literatur...

Of the proposed causes and associations of nonuremic calciphylaxis, IgA is not included. We encountered a 60-year-old Hispanic female with stage III chronic kidney disease secondary to IgA nephropathy, who presented with a painful abdominal eschar. The diagnosis of nonuremic calciphylaxis was made, with IgA nephropathy being the most interesting potential cause. Our case represents the first re...

Acute phosphate nephropathy or nephrocalcinosis is a tubulointerstitial nephropathy characterized by tubular calcium phosphate deposition - crystal nephropathy - and slowly progressive renal insufficiency during or following treatment with preparations containing sodium phosphate. We report a patient who developed nephrocalcinosis (crystal induced acute kidney injury) following the administrati...

Diabetic nephropathy is a significant cause of chronic kidney disease and end-stage renal failure globally. Much research has been conducted in both basic science and clinical therapeutics, which has enhanced understanding of the pathophysiology of diabetic nephropathy and expanded the potential therapies available. This review will examine the current concepts of diabetic nephropathy managemen...

Urethral amyloidosis is a rare condition that can cause hematuria and urinary obstruction symptoms. While there is no established association between immunoglobulin A (IgA) nephropathy and secondary amyloidosis, which is typically found in chronic inflammatory conditions, it is hypothesized that IgA nephropathy may be a systemic condition with inflammatory mediators. We present a case of urethr...

BACKGROUND The progression and complications of chronic kidney disease should differ depending on the cause (C), glomerular filtration rate category (G), and albuminuria (A). The KNOW-CKD (KoreaN Cohort Study for Outcome in Patients With Chronic Kidney Disease), which is a prospective cohort study, enrolls subjects with chronic kidney disease stages 1 to 5 (predialysis). METHODS/DESIGN Nine n...

We reported here a case of anticoagulant-related nephropathy (ARN) in an elderly patient with background history chronic kidney disease (CKD-stage 4, estimated glomerular filtration rate (eGFR) <24 ml/min). He presented acute injury on (AKI/CKD) eGFR 9 ml/min and serum creatinine 6.0 mg/dl.

The aim of the study was to evaluate the evolution of glomerular volume 4 months after transplantation. Mean glomerular volume (Vg) was estimated according to the Weibel and Gomez method in a donor and a protocol biopsy done at 139 +/- 58 d in 41 stable grafts. Biopsies were also evaluated according to the Banff schema. Vg increased after transplantation from 4.1 +/- 1.4 to 5.1 +/- 2.4 x 10(6) ...