in this study the original mitotic chromosome counts are presented for 5 onobrychis species of o. sect. onobrychis in iran, 2n = 2x = 14 for o. persica, 2n = 4x = 28 for o. viciifolia, 2n = 4x = 28 for o. altissima, 2n = 2x = 14 for o. shahpurensis and 2n = 2x = 14 for o. sosnovskyi. the basic chromosome numbers of all studied taxa are consistent with the proposed base number of x = 7. in addit...

a large number of simple or complex translocation involving the cml and aml chromosomal abnormalities has been described. this study was aimed to investigate the complex chromosome aberrations in the series of myeloid malignancies including cml and aml. the present report deals analyzed 187 consecutive with cml and aml patients, using methotrexate  cell synchronization and  un-stimulated cultur...

autism is a complex neuropsychiatric disorder that manifests in early childhood. although the etiology is unknown yet but, new hypothesis focused on identifying the key genes related to autism may elucidate its etiology. the main objective of the present study was to verify the value of karyotyping in autistic children and identifying association between chromosome abnormalities and autism.we e...

Cytogenetic studies of rat neurogenic tumor lines induced by ethylnitrosourea (ENU) have shown specific involvement of chromosome 4. The study reported here further characterizes the association of chromosome 4 abnormalities in rat tumor cell lines with regard to etiological agent, tissue of origin, and tumorigenic potential of cloned lines. Lines from rat gliomas induced by avian sarcoma virus...

background: genome instability is a main cause of chromosomal alterations in both somatic and germ cells when exposed to environmental, physical and chemical genotoxicants. germ cells especially spermatozoa are more vulnerable to suffering from dna damaging agents during spermatogenesis and also more potent in transmitting genome instability to next generation. methods: to investigate the effec...