نتایج جستجو برای: chromodomain y cdy1

تعداد نتایج: 494674  

Journal: :Chemical communications 2016
Yan-Jiun Lee M J Schmidt Jeffery M Tharp Annemarie Weber Amber L Koenig Hong Zheng Jianmin Gao Marcey L Waters Daniel Summerer Wenshe R Liu

Fluorophenylalanines bearing 2-5 fluorine atoms at the phenyl ring have been genetically encoded by amber codon. Replacement of F59, a phenylalanine residue that is directly involved in interactions with trimethylated K9 of histone H3, in the Mpp8 chromodomain recombinantly with fluorophenylalanines significantly impairs the binding to a K9-trimethylated H3 peptide.

2009
Achim Leutz Ansgar Klebes

Drosophila polytene chromosomes are compacted into a series of bands and interbands. Z4 is a protein to keep this pattern of polytene chromosomes, since Z4 mutant larvae show a decompaction of chromosomes and a loss of banding pattern (Eggert et al., 2004). By coimmuno-precipitation, we identified a chromodomain protein, which we named Chriz, for chromodomain protein interacting with Z4 (Gortch...

Journal: :Human molecular genetics 2003
Steve Dorus Sandra L Gilbert Michele L Forster Robert J Barndt Bruce T Lahn

Theories predict that the long-term survival of duplicated genes requires their functional diversification, which can be accomplished by either subfunctionalization (the partitioning of ancestral functions among duplicates) or neofunctionalization (the acquisition of novel function). Here, we characterize the CDY-related mammalian gene family, focusing on three aspects of its evolution: gene co...

2009
Jenny Alfredsson-Timmins Mayumi Ishida Jun-ichi Nakayama Pernilla Bjerling

The chromatin in the cell nucleus has a spatial organisation. For example, in the fission yeast, Schizosaccharomyces pombe, transcriptionally repressed heterochromatin is found at the nuclear membrane (NM). The centromeres and the mating-type region localise in the proximity of the spindle pole body (SPB), while the telomeres are found on the opposite side of the nucleus in the proximity of the...

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