نتایج جستجو برای: chromenes
تعداد نتایج: 289 فیلتر نتایج به سال:
a simple, mild and high efficient procedure for one pot three component synthesis of 2-amino 4-h chromene derivatives was studied. the reaction was performed in water using aryl aldehydes, malononitrile and resorcinol, phloroglucinol or naphthole in the presence of n-methyl d-glucamine (meglumine) as a green high efficient catalyst. the reaction was studied in thermal, microwave (mw) and ultras...
BACKGROUND Sixteen 3-styryl-2H-chromenes were subjected to quantitative structure-activity relationship analysis based on their cytotoxicity, tumor selectivity and anti-HIV activity, in order to find their new biological activities. MATERIALS AND METHODS Cytotoxicity against four human oral squamous cell carcinoma (OSCC) cell lines, three mesenchymal and two epithelial normal oral cells was d...
The synthesis of 2-amino-2-chromenes under solvent-free conditions is disclosed here using a silica triflate catalyzed one-pot three component condensation. product was obtained in outstanding yield the optimal reaction range functionalized aromatic aldehydes, malononitrile, and α/β-naphthol. This procedure stands out for its wide substrate scope, reduced time, great yield, functional group com...
background: recently, the anti cancer effect of chromene derivatives in different cell types has been reported. in this study, we report some derivatives of dihydropyrano[c]chromenes with growth inhibitory and apoptotic activity against k562, chronic myeloid leukaemia (cml). methods: the cells were seeded in 96-well plates at 1×105 cells/well and treated with different concentrations of the dih...
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