leiomyoma is a very rare intraocular tumor, which can occur in the iris, ciliary body and choroids. we report a case of choroidal leiomyoma in a 16-years old women whose left eye was enucleated because of clinical suspicion for melanoma. using conventional light microscopy tumor was interpreted as spindle cell tumor, most probably of neurogenic origin and after using immunohistochemical studies...

PURPOSE To report three low-passage cell lines from primary choroidal melanoma with metastatic outcome, which were stable for cytogenetic patterns and expression profiles of the primary melanoma. METHODS In patients with choroidal melanoma, transscleral fine needle aspiration biopsy (FNAB) was performed immediately before plaque placement for (125)iodine brachytherapy or immediately after enu...

bling times in metastatic malignant melanoma of the uvea: tumor progression before and after treatment. Ophthalmology. 2000;107(8):1443-1449. 8. Clarke M, Collins R, Darby S, et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;366(9503):2087-2106. 9. Presch...

performed. Previous cases of vitelliform retinopathy have had some clinical findings consistent with MAR, while others have not. None of these reports had clinical evidence of choroidal involvement. The vitelliform lesions have been postulated to represent a new paraneoplastic clinical manifestation. The pathologic results in this case argue against a paraneoplastic entity but may suggest a loc...

PURPOSE To report a case of diffuse peripapillary choroidal melanoma which began as a small choroidal nevus and was successfully treated with gamma knife radiotherapy. METHODS Observational case report. RESULTS A 31-year-old visually asymptomatic man presented for a routine eye examination and was noted to have a small choroidal nevus. Six years later, the lesion had become a diffuse juxtap...

A 61-year-old woman developed blurred vision in her left eye in December 2006. A clinical diagnosis of choroidal melanoma was made. The patient underwent excision of the left lens, followed by vitrectomy and stereotactic radiotherapy. She remained systemically healthy until 50 months later when, during a CT scan done for staging purposes, a newly visible lump was noted in the lower quadrant of ...

BACKGROUND Choroidal melanoma is the most common primary malignancy of the eye. Enucleation has been the mainstay of treatment, but new and more effective options have recently been proposed as eye- and vision-sparing alternatives. METHODS We reviewed the medical literature for trials and case reports involving the evolution, current uses, and limitations of alternatives to enucleation for tr...

PURPOSE/METHODS To report a rare case of melanocytoma in a choroidal location. The clinical and echographic characteristics were similar to those of a melanoma. The treatment selected in our case was a choroidectomy. Tissue was stained with hematoxylin-eosin, periodic acid-Schiff, Masson's trichromic and immunohistochemistry was performed. RESULTS/CONCLUSIONS The clinical and histopathologic ...