The role of virus-infected mononuclear leukocytes (MNLs) in the pathogenesis of neonatal herpetic chorioretinitis in newborn rabbits was investigated. As early as 2 days after inoculating the animals' skins with type 2 herpes simplex virus (HSV-2), infectious MNLs in the infected animals' peripheral blood were found. The virus was associated, for the most part, with MNLs that belonged to phagoc...

A 48-year-old man presented with visual dimness in the right eye that had developed 2 weeks previously. Dilated fundus examination showed few vitreous cells and numerous yellow, placoid lesions in both eyes. His right eye had more severe serous retinal detachment involving the macula. Fluorescein angiography demonstrated early irregular hypofluorescence with late staining in the areas of the ye...

We describe a renal transplant patient with a primary Toxoplasma gondii infection presenting as pneumonitis, with subsequent chorioretinitis and encephalitis. The diagnostic challenges of T. gondii infection in immunocompromised patients are discussed.

Purpose To compare the effectiveness of quadruple-drug therapy consisting of cotrimoxazole (trimethopin and sulfamethoxazole), clindamycin antibiotics, and oral corticosteroid versus triple therapy consisting of pyrimetamine, sulphadiazine, and oral corticosteroid in the resolution of toxoplasmic chorioretinitis. Methods This was a double-blind randomized controlled trial with repeated measur...

BACKGROUND The evaluation of toxoplasma chorioretinitis is of utmost importance in the early diagnosis, treatment, and prevention of visual problems that can otherwise lead to permanent blindness. The aim of this study was to determine the prevalence of toxoplasma chorioretinitis among primary school students in Tehran. MATERIAL/METHODS This cross-sectional study involved 1529 healthy primary...

Preliminary Report THE first report on the use of cryosurgery in cataract extraction was made by Krwawicz (1961); since then he has reported 660 extractions performed by this method. Kelman and Cooper (1963) have described its use in an unspecified number of.cases which included subluxated lenses and dislocated lenses. Bellows (1964) reported 6 cases. Rosengren (1965) gave the results of 120 cr...

BACKGROUND Acute maculopathy is a rare condition of unknown aetiology and Coxsackie virus is known to be associated with this macular chorioretinitis. FINDINGS We report a case of acute unilateral maculopathy in a 35-year-old woman with concurrent hand foot and mouth disease. Furthermore, we display multimodal imaging (colour fundus photographs, autofluorescence, spectral domain ocular cohere...

Chorioretinitis occurred in a young man whose long-standing cryptococcal meningitis had been identified and treated. In one eye spontaneous resolution had occurred. His case history and fluorescein angiograms are presented.