Gyrate atrophy is a rare metabolic disease with autosomal recessive inheritance pattern characterised by hyperornithinemia and typical ocular findings. This report presents a 17-year-old intellectually challenged girl consulting for a progressive fall of visual acuity with night blindness. Fundus examination showed patches of chorioretinal atrophy with typical scalloped borders and peri vascula...

AIMS To investigate the impact of the macrofilaricidal drug, amocarzine, on the evolution of chorioretinopathy in onchocerciasis. METHODS A prospective uncontrolled cohort study was performed using subjects infected with Onchocerca volvulus in a hyperendemic onchocerciasis focus in Esmeraldas Province in Ecuador. Study subjects were recruited into four cohorts in which ophthalmic and parasito...

Thioridazine toxicity has been described as a 'progressive chorioretinopathy', but this designation can be misleading. During the first year after thioridazine exposure retinal pigmentation evolves from a granular to a patchy or nummular appearance. However, visual function and the electroretinogram typically improve during this period. Some cases may show chorioretinal atrophy and functional l...

BACKGROUND For diagnosis and follow-up of glaucoma an exact evaluation of the optic nerve disc and the nerve fiber layer is necessary. METHODS The slit-lamp evaluation of the optic nerve disc and nerve fiber layer is presented as well as the evaluation with the Nerve Fiber Analyzer and the Heidelberg Retina Tomograph. RESULTS Signs of a glaucomatous optic disc include a difference of more t...

West Nile Virus (WNV), first isolated in 1937 in the West Nile district of Uganda, is a single-stranded RNA flavivirus. It is a member of the Japanese encephalitis serogroup. WNV infection is a zoonotic disease transmitted by a mosquito vector (type Culex), with wild birds serving as its reservoir. The disease is endemic in Europe, Australia, Asia, Africa, and North and Central America since it...

The case of a 5-month-old black female child with a linear sebaceous naevus syndrome and multiple congenital anomalies is presented. Ocular malformations consisted of colobomatous changes of the lid and retina, dermoid of the conjunctiva, chorioretinal changes, and peripapillary atrophy of the optic nerve. Systemic findings included midline cleft of the secondary palate with involvement by the ...

This case study focuses on keratopathy and chorioretinopathy resulting congenital syphilis. The patient is a 51-year-old man who had diabetes mellitus for eleven years. Furthermore he had interstitial keratitis due to syphilis. Both fundi showed chorioretinal atrophy. The fundus findings were similar to those of retinitis pigmentosa. We examined the visual field, ERG and dark adaptation. The se...

Morning glory syndrome (MGS) is a rare congenital optic disc anomaly characterized by a funnel-shaped, excavated optic disc surrounded by chorioretinal pigmentary disturbance. The main ophthalomoscopic feature of the MGS is enlarged optic disc with a funnel shaped scleral defect; elevated peripapillary chorioretinal pigmentation; and pale fluffy tissue of glial hyperplasia overlying the optic d...

Parapapillary chorioretinal atrophy is a morphological feature of glaucomatous optic nerve damage since it occurs more often and is larger in glaucomatous eyes than in normal eyes. This study was undertaken to find the histological correlation. Optic disc photographs and histological sections through the optic disc of 21 human eyes enucleated because of malignant uveal melanoma were morphometri...