نتایج جستجو برای: chitosan particles
تعداد نتایج: 172947 فیلتر نتایج به سال:
BACKGROUND Chitosan nanoparticles have become of great interest for nanomedicine, biomedical engineering and development of new therapeutic drug release systems with improved bioavailability, increased specificity and sensitivity, and reduced pharmacological toxicity. The aim of the present study was to synthesis and optimize of the chitosan nanoparticles for industrial and biomedical applicati...
BACKGROUND The purpose of this study is to modulate the transfection efficiency of adenovirus (Ad) on the cornea by the covalent attachment of chitosan on adenoviral capsids via a thioether linkage between chitosan modified with 2-iminothiolane and Ad cross-linked with N-[gamma-maleimidobutyryloxy]succinimide ester (GMBS). METHODOLOGY/PRINCIPAL FINDINGS Modified Ad was obtained by reaction wi...
The chitosan nanoparticles used widely as a drug delivery systems recently. In the present study the Echis carinataus snake venom loaded chitosan nanoparticles were prepared based on ionic gelation of tripolyphosphate and chitosan. The nanoparticles physicochemical characteristics, stability and biological activity of encapsulated venom were studied. The particles were spherical in shape and th...
Due to the existence of new methodologies that have reduced the production costs of microbiological chitosan, this paper puts forward the use of agro-industrial residues in order to produce microbiological chitosan and to apply chitosan as an innovative resource for removing acid orange 7 (AO7) from wastewaters. The best culture conditions were selected by a full 24 factorial design, and the re...
Background & Aims: In recent years, the feasibility of hydrophilic nanoparticles has been broadly investigated for use in drug delivery and therapeutic systems. Due to the problems of traditional adjuvants, in this study Agkistrodon halys (Ah) Snake venom was loaded in chitosan nanoparticles (CS NPs) in order to be used as an advanced adjuvant and antigen delivery system in ant...
The presence of contaminants in wastewater poses significant challenges to water treatment processes and environmental remediation. The use of coagulation-flocculation represents a facile and efficient way of removing charged particles from water. The formation of stable colloidal flocs is necessary for floc aggregation and, hence, their subsequent removal. Aggregation occurs when these flocs f...
Since maleic acid is capable of specially dissolving Chitosan, in this research the method of producing water lubricant nanoparticles in Chitosan solution, based on maleic acid has been studied. The resulting nanoparticles have a remarkable contact surface with the ordinary Chitosan form in absorbing metal ions, proteins and fat existing in Whey. After providing the 0.02, 0.03, 0.05 gr. density...
BACKGROUND Although there are a number of reports regarding the toxicity evaluation of inorganic nanoparticles, knowledge on biodegradable nanomaterials, which have always been considered safe, is still limited. For example, the toxicity of chitosan nanoparticles, one of the most widely used drug/gene delivery vehicles, is largely unknown. In the present study, the zebrafish model was used for ...
Naturally occurring polysaccharides such as alginic acid and chitosan have been recognized as one of the most effective adsorbents to eliminating low levels of heavy metal ions from waste water stream. The present study intended to use alginic acid and chitosan simultaneously, which are expected to form a rigid matrix structure of beads due to electrostatic interaction between carboxyl groups o...
In this paper, ultrafine particles of crystalline hydroxyapatite were synthesized by hydrothermal treatment at 180C, and the surface of hydroxyapatite particles was modified by hexametaphosphate for the excellent dispersion properties of HA in the scaffolds. The phase separation was used to fabricate the scaffolds of polycaprolacton/chitosan and hydroxyapatite/polycaprolacton-chitosan. The effe...
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