Biowaste originating from aquaculture sector represents a potential feedstock to produce value-added substances and materials like chitin chitosan. They are the long chain polymers of N-acetylglucosamine with huge industrial biomedical significance. Chitin has been recognized as useful biomaterial for drug delivery neurological therapy. Similarly, chitosan oligosaccharide, short polymer derived...

Abstract Chitosan is a polysaccharides compound derived from nature and has an amine group hydroxyl that gives it unique physicochemical properties, which are polychationic chelating agent. This shows chitosan can be used as stabilizer reducer of Ag nanoparticles. Unlike other studies, was in this study Black Soldier Fly exuviae been through demineralization, deproteination, depigmentation, dea...

Preparation of poly (ethylene glycol) (PEG)-grafted chitosan is essential for improving the biocompatibility and water solubility of chitosan. Presently available methods for this have limitations. This article describes a new method for preparing PEGylated chitosan nanoparticles. For this chitosan was chemoselectively modified using a novel scheme at the C6 position of its repeating units by P...

Since maleic acid is capable of specially dissolving Chitosan, in this research the method of producing water lubricant nanoparticles in Chitosan solution, based on maleic acid has been studied. The resulting nanoparticles have a remarkable contact surface with the ordinary Chitosan form in absorbing metal ions, proteins and fat existing in Whey. After providing the 0.02, 0.03, 0.05 gr. density...

BACKGROUND AND THE PURPOSE OF THE STUDY Studies show that chitosan nanoparticles increase mucoadhesivity and penetration of large molecules across mucosal surface. The aim of the present study was to investigate the use of thiolated chitosan in the development of polysaccharide-coated nanoparticles in order to confer specific functionality to the system. METHODS Methyl methacrylate nanopartic...

BACKGROUND Chitosan has gained considerable attentions as a biocompatible carrier to improve delivery of active agents. Application of this vehicle in the form of nanoparticle could profit advantages of nanotechnology to increase efficacy of active agents. The purpose of this study was to provide detailed information about chitosan-glutathione (Cht-GSH)nanoparticles which are gaining popularity...

The oncogene c-Jun has been found to be up-regulated in a variety of cancers, including osteosarcoma. Doxorubicin is a frontline chemotherapeutic against osteosarcoma, but is limited by toxicity. DNAzymes are oligonucleotides capable of specific catalysis of target mRNA. A biocompatible c-Jun DNAzyme nanoparticle formulated from chitosan regressed the growth and metastasis of pre-established tu...

Ionotropic gelation between chitosan, as the polycation of acidic pH, and TPP (penta sodium triphosphate aka tripolyphosphate) as the anionic oligomeric partner leads to the formation of colloidal systems which can range from approximately 100nm to 2000nm. Depending on the conditions, particles with different properties can be obtained including differences in size, zeta potential, stability at...

Chitosan, a natural polymer, is a promising system for the therapeutic delivery of both plasmid DNA and synthetic small interfering RNA. Reports attempting to identify the optimal parameters of chitosan for synthetic small interfering RNA delivery were inconclusive with high molecular weight at high amine-to-phosphate (N:P) ratios apparently required for efficient transfection. Here we show, fo...