Background Calprotectin is a cytosolic protein that belongs to the S-100 protein group with immunomodulatory and antiproliferative actions. The level of this protein increases in infection, inflammation, and malignancy. The aim of this study was to evaluate the level of...

  Background Endothelial Cell-Specific Molecule-1 (ESM-1) is a 50 kDa soluble proteoglycan that is produced mainly the vascular endothelial cells of the kidney and lung. It is produced by the effects of proangiogenic and pro-inflammatory cytokines, and it indicates activation and dysfunction of the vascular endothelium. We aimed to detect the role of ESM-1 in childre...

Background: Asthma is the most common chronic disease of childhood, which is increasing in prevalence worldwide. Parents try to find the ways to overcome their anxiety of chronic diseases such as asthma. This study was designed to determine the effect of massage therapy for children on anxiety level of mothers with asthmatic children. Aim: This study aimed to determine the effect of combined ma...

this study investigated the association between hsv-1 infection and atopy by comparing seropositivity to hsv-1 in atopic children with asthma and allergic rhinitis and in non-atopic children. totally 249 children randomly selected from the university outpatient pediatric clinics were prospectively enrolled in the study between september 1 and november 30, 2007. serum samples were examined using...

Asthma is the most common cause of recurrent wheezing, cough and dyspnea in childhood. Delay in diagnosis and lack of appropriate treatment can cause sustained changes which decrease respiratory capacity of children in future. Therefore, identifying the symptoms relating to asthma is the key for timely diagnosis and treatment of this disease. This study was done to investigate asthma incidence ...

Background: IL-17 is a major cytokine player in T cell mediated leukocyte associated inflammation. IL-17 is also recognized to participate in the pathophysiology of asthma. Objective: To determine the role of IL-17 in predicting severe asthma. Methods: We obtained serum samples from asthmatic children under the age of 5-year in three different groups of mild (n=33), moderate (n=28) and severe (...

background: allergic diseases including asthma, allergic rhinitis (ar) and eczema are common chronic diseases in children. the purpose of this study was to determine the prevalence of asthma, ar and eczema in sari, iran. methods: this study was carried out on all elementary schools selected as a cluster from february 2010 to july 2010 in sari, north of iran. a questionnaire was provided accordi...

Introduction  Metered Dose Inhalers (MDIs) are the most common drugs for the control of asthma. This study was conducted to evaluate usage patterns, satisfaction with and concerns about MDIs for children with asthma and the related factors from the viewpoints’ of their parents. Materials and methods This cross-sectional study was conducted on children with asthma who referred to asthma and a...

Background: Allergic diseases including asthma, allergic rhinitis (AR) and eczema are common chronic diseases in children. The purpose of this study was to determine the prevalence of asthma, AR and eczema in Sari, Iran. Methods: This study was carried out on all elementary schools selected as a cluster from February 2010 to July 2010 in Sari, North of Iran. A questionnaire was provided accordi...