BACKGROUND Abuse in childhood is associated with many negative adult health outcomes. Only 1 study to date has found an association between childhood abuse and cancer. By using a regionally representative community sample, this preliminary study sought to investigate the association between childhood physical abuse and cancer while controlling for 3 clusters of risk factors: childhood stressors...

Twenty-five years ago, Sir Richard Doll and Sir Richard Peto estimated in their landmark monograph, The Causes of Cancer, that 75% to 80% of adult cancer could be attributed to lifestyle choices and environmental exposures.1 In stark contrast, elucidating the causes of childhood cancer remains one of the most vexing questions in medicine. Despite progress in identifying the molecular causes of ...

The majority of children with cancer live in low- and middle-income countries (LMICs) with little or no access to cancer treatment. The purpose of the paper is to describe the current status of childhood cancer treatment in Africa, as documented in publications, dedicated websites and information collected through surveys. Successful twinning programmes, like those in Malawi and Cameroon, as we...

BACKGROUND Little is known about the causes of childhood cancer, partly as not many children develop cancer, although childhood cancer is a leading cause of death by disease in the young. The young age of the children suggests that risk factors for childhood cancer may be present during pregnancy. Previous studies have shown that exposure to trans-fat, a type of unsaturated fat common in indust...

abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. we report an 11 years old girl who developed central hypothyroidism and acth deficiency during the chemotherapy for cns relapse of acute lymphoblastic leukemia before receiving radiotherapy. keywords: thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leuk...

Parental exposure to pesticides may contribute to childhood cancer risk. Through the Agricultural Health Study, a prospective study of pesticide applicators in Iowa and North Carolina, we examined childhood cancer risk and associations with parental pesticide application. Identifying information for 17,357 children of Iowa pesticide applicators was provided by parents via questionnaires (1993-1...

This case-control study in Shiraz aimed to determine the relationship between parental smoking and childhood cancer. A questionnaire was completed by the mothers of 98 children newly diagnosed with cancer before the age of 14 years and 100 age- and sex-matched controls. Maternal smoking (prior to and during pregnancy and after the birth), and the numbers of maternal cigarettes smoked were not a...

Background: Leukemia is the most common cancer in children. We aimed to evaluate the association between exposure to magnetic fields and childhood leukemia. Materials and Methods: In this overview,the relevant articles evaluating the association between exposure to magnetic fields...

BACKGROUND Childhood cancer is rare, but there are now good survival prospects and in the UK approximately 1 in 1,000 young adults is a survivor of childhood cancer. There are many adverse health outcomes associated with the treatment of childhood cancer often arising several years after completion of treatment. The aim of this study was to quantify the long-term clinical follow-up practices co...

BACKGROUND The relationship of childhood socioeconomic position (SEP) to adult cancer has been inconsistent in the literature and there has been no review summarising the current evidence focused solely on cancer outcomes. METHODS AND RESULTS We performed a rapid review of the literature, which identified 22 publications from 13 studies, primarily in the UK and northern European countries tha...