Vol.31, No. 4, 1985 649 tecting hypercholesterolemia must have the best possible analytical performance. We suggest that, in screening a population for hypercholesterolemia, serum or plasma samples are preferable to blood spots on fiter paper. Instruments such as the Cobas-Bio centrifugal analyzer require less than 50 L of sample and the typical overall CV is 4% for assays of cholesterol in pla...

OBJECTIVES Collection of physical measurements and biospecimens in the home may be an efficient way to obtain objective health measurements. This study assesses differences between collection in the home and a standardized setting. METHODS Participants had physical measurements and biospecimens taken in the National Health and Nutrition Examination Survey mobile examination center (MEC). Then...

An important motivation for the construction of biobanks is to discover biomarkers that identify diseases at early, potentially curable stages. This will require biobanks from large numbers of individuals, preferably sampled repeatedly, where the samples are collected and stored under conditions that preserve potential biomarkers. Dried blood samples are attractive for biobanking because of the...

Acromegaly is a systemic syndrome caused by overproduction of growth hormone. The syndrome affects cutaneous, endocrine, cardiovascular, skeletal, and respiratory systems. Cutaneous manifestations of acromegaly are various, usually being the first presenting findings of the disease. Forty-nine patients with acromegaly, followed-up at a tertiary referral hospital, underwent dermatological examin...

We report the case of a 35-year-old woman with deep-red asymptomatic macules on the plantar and dorsal skin of the right great toe. Histopathologic findings were compatible with Angioma serpiginosum. Immunohistochemical stains for estrogens and progesterone receptors were negative. Dermoscopy showed an erythematous parallel ridge pattern with double rows of irregular dots and globules. We repor...

BACKGROUND Iraq used chemical weapons against thousands of Iranian militaries and civilians. This study aimed to compare the chronic cutaneous side effects of exposure to sulfur mustard (SM) with nerve agents (NA). METHODS The study enrolled 154 SM exposed cases and 175 (NA) exposed cases. Presence of any late cutaneous manifestations was evaluated by a dermatologist via prior history of acut...

Skin diseases are a global health problem that is difficult to diagnose sometimes due the disease’s complexity, and time-consuming effort. In addition fact skin affect human health, it also affects psycho-social life if not diagnosed controlled early. The enhancement of images processing techniques machine learning leads an effective fast diagnosis help detect disease This paper presents model ...

Objective. To investigate the relationship between IGF-I and the nutritional status of West-African children hospitalised for nutritional rehabilitation. Patients and methods. A cohort study was performed in two centres for nutritional rehabilitation and education (CREN) in Burkina Faso. Children were followed and the anthropometric data as well as the capillary blood samples were taken on the ...

Dried blood spots collected on Specimen Collection Cards, commonly called “Guthrie cards” (Figure 1), have been used widely as valuable resources for genetic studies, such as, determination of hereditary diseases like phenylketonuria and congenital hypothyroidism. The ease of storage and transportation of these cards with blood spots also lends them to a variety of large field studies, especial...