Neural mechanisms underlying the onset and maintenance of epileptic seizures involve alterations in inhibitory and/or excitatory neurotransmitter pathways. Thus, the prospecting of novel molecules from natural products that target both inhibition and excitation systems has deserved interest in the rational design of new anticonvulsants. We isolated the alkaloids (+)-erythravine and (+)-11-α-hyd...

Oxidative stress remains one of the most well studied, albeit somewhat contentious, causes of age-related changes in humans. Consequently, a large number of putative antioxidant compounds are freely available in myriad formulations that are often not tested for their efficacy or regulated for quality control. Following the development of a Drosophila model of oxidative-stress dependent aging (p...

Pongamia pinnata is a marsh growing Indian tree. Its seeds are used in febrile and inflammatory diseases in Indian system of medicine. Previous preliminary studies with ethanolic seed extract of this plant had exhibited an anti-inflammatory effect in rat. Different solvent fractionated extracts were evaluated in the present study for anti-inflammatory effect in chemically induced paw inflammati...

enzymatic deinking of xerox printed papers by commercial cellulase from aspergillus niger fungi was investigated. enzymatic treatment was done under constant condition of 0.1 percent enzyme based on oven-dried weight of pulp (102 unit per 100 gram oven-dried pulp), 15 min. treatment time, in four ph levels as 4, 5.7, 8 and 9. then, the effect of ph variation on the appearance and strength prope...

objective: sleep complaints are common among iranian chemically-injured veterans. the growing body of research has investigated (in) equalities between such subjective complaints and objective sleep records. moreover, sleep complaints are associated with depressive symptoms. depressive symptoms, also, have been frequently reported in chemically-injured veterans. therefore, the purpose of this p...

abstract background: mustard gas, lethal in high doses, affects multiple organs such as skin, eye and respiratory system. we studied the development of late onset mustardinduced polyneuropathy among chemically wounded iranian veterans. methods: in this descriptive study, 100 chemically wounded iranian veterans with severe eye involvement were examined for any signs and symptoms of polyneuropath...

To account for the range of stellar metallicities in local galaxies and for the increasing importance of low metallicities at higher redshift we present chemically consistent models for the spectral and chemical evolution of galaxies over cosmological timescales. We discuss advantages, limitations and future prospects of our approach.

Background: During imposed war (1980-1988) Iraq frequently used chemical warfare particularly mustard gas. Skin is frequently involved in victims. Objective: Our main objective was to evaluate chronic skin manifestations due to exposure to mustard gas 10-19 years after exposure in a case-control study. Patients and Methods: 101 chemically wounded combators and 121 non-chemically wounded c...