BACKGROUND It is suggested that disturbed CSF dynamics are involved in the pathophysiology of idiopathic normal pressure hydrocephalus (INPH). The pulsatility curve describes the relationship between intracranial pressure (ICP) and the amplitude of cardiac related ICP pulsations. The position of baseline ICP on the curve provides information about the physiological state of the CSF dynamic syst...

INTRODUCTION Tyrosine kinase inhibitors (TKI) are medications of interest in the treatment of Systemic Sclerosis (SSc) because of their ability to inhibit pathways involved in fibrosis. In this open-label pilot trial, our objectives were to assess the safety, efficacy, and molecular change associated with treatment of patients with diffuse cutaneous (dc)SSc with the TKI nilotinib (Tasigna™). ...

Vegetable oil derived fuels for diesel engines are becoming important as alternative to petroleum diesel fuels due to their environmental friendliness and availability. Ignition quality in compression ignition (CI) engines is influenced by thermal characteristics and fuel properties. In this study, the effects of vegetable oil transesterification and vegetable oil-1-butanol-diesel blend on fuel...

In recent days, fossil fuel resources are decreasing day by day while the population number is continually increasing. This is why many researchers make their efforts to find new sources of energy, especially the renewable ones to compensate the deficiency of fossil energy. Biodiesel fuels are making its place as a key future renewable source and are attracting increasing attention worldwide as...

Goal. To analyze the qualitative characteristics of local raw materials different origins and assess prospects its rational use as a source organic matter for production various types improvers secondary in Ukraine soil improvers, Methods. Laboratory — study agrochemical properties main materials, conducted according to certified methods, followed by statistical data processing. Results. The ar...

This study assessed the sustained effect of a physical activity (PA) counseling intervention on PA one year after intervention, predictors of sustained PA participation, and three classes of post-intervention PA trajectories (improvers, maintainers, and decliners) in 238 older Veterans. Declines in minutes of PA from 12 to 24 months were observed for both the treatment and control arms of the s...

The years immediately following the widespread interest in patient safety and then healthcare quality saw considerable debate between pragmatically oriented improvers and research-oriented evaluators —or between ‘evangelists’ and ‘snails’ as one longtime observer characterised the two groups. Too often, enthusiastic improvers (‘evangelists’) relied on simple pre-post designs within a single con...