نتایج جستجو برای: certolizumab pegol
تعداد نتایج: 885 فیلتر نتایج به سال:
Over the past decade, treatment of rheumatoid arthritis (RA) has been revolutionized with the introduction of biological disease-modifying antirheumatic drugs (DMARDs), such as TNF inhibitors (e.g., infliximab, etanercept, adalimumab, golimumab and certolizumab pegol), the IL-6 receptor inhibitor tocilizumab, the chimeric anti-CD20 monoclonal antibody rituximab and the T-cell costimulation inhi...
The development of tumor necrosis factor (TNF) inhibitor therapy has revolutionized the treatment of rheumatoid arthritis (RA). Unfortunately, no one single agent is fully effective in every patient; different patients respond to different therapies in different ways, even to those agents with the same mechanism of action. In this regard, newer TNF inhibitor agents, such as golimumab and certol...
Objective The aim was to assess the long-term safety and efficacy of certolizumab pegol over 4 years of continuous treatment in patients with axial spondyloarthritis (axSpA), including both AS and non-radiographic (nr-) axSpA. Methods RAPID-axSpA was a phase 3 randomized trial, double blind and placebo controlled to week 24, dose blind to week 48 and open label to week 204. Patients had a cli...
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