Administration of L-arginine has been shown to increase cerebral blood flow and reduce neurological damage after experimental traumatic brain injury. The purpose of this study was to examine the optimal dose and time window for these neuroprotective effects. In a dose response experiment, doses of L-arginine ranging from 37.5 to 600 mg/kg were administered 5 min after a 5-m/s, 3-mm, controlled ...

Summary A 3‐year‐old Thoroughbred mare found recumbent in the field was referred for further assessment with suspicion of a skull fracture. Neurological examination identified compulsive tight circling to left, and hypermetria all four limbs. The obtunded, mild head tilt right, absent menace response right eye decreased facial sensation on right. Standing computed tomographic revealed subtle de...

Approximately 1.7 million people sustain a traumatic brain injury (TBI) each year, with motor vehicle crash (MVC) representing the leading cause for TBI-related hospitalization. Subarachnoid hemorrhage (SAH), subdural hematoma (SDH), cerebral contusion, and diffuse axonal injury (DAI), are some of the most common and serious consequences of MVC-related TBI and are associated with high mortality...

BACKGROUND Reduction of cerebral blood flow plays a crucial role in causing posttraumatic cerebral ischemia. However, the methodologic adequacy of studies from which currently used cerebral blood flow thresholds in traumatic brain injury have been derived has not been evaluated. OBJECTIVE To systematically evaluate the evidence available on cerebral blood flow thresholds and its methodologic ...

Posttraumatic cerebral infarction is a recognized complication of craniocerebral trauma, but its frequency, cause, and influence on mortality are not well defined. To ascertain this information, all cranial CT studies demonstrating posttraumatic cerebral infarction and performed during a 40-month period at our trauma center were reviewed. Posttraumatic cerebral infarction was diagnosed by CT wi...

to identify anatomic and physiologic characteristics of children which are different from adults and to explain major patterns and responses of different types of injuries and to apply atls principles in management of injured kids and to emphasize on injury prevention to reduce the impact of injury in children. children have larger head, smaller jaw, shorter, narrower, funnel shaped airway, sof...

TOPIC: Cardiovascular Disease TYPE: Medical Student/Resident Case Reports INTRODUCTION: The right ventricle is the most proximal cardiac structure to chest wall and commonly injured during motor vehicle accidents blunt trauma. However, isolated ventricular failure an uncommon presentation of Here we report a case heart cardiogenic shock in setting trauma myocardial contusion. CASE PRESENTATION:...