The left cerebral hemisphere of Mongolian gerbils was used to elucidate the mechanisms of brain edema which develop during cerebral ischemia and after restoration of cerebral blood flow following temporary ischemia. Water content was measured by the tissue-drying method. Sodium and potssium ion concentration was measured by flame photometry. Passage of 131I-albumin (RISA) from blood to the cere...

Cerebral hyperperfusion syndrome is a rare but serious complication of carotid revascularization, and characterized by ipsilateral headache, hypertension, seizures, focal neurological deficits. Therefore, treatment strategies are directed towards regulation blood pressure limitation rises in cerebral perfusion to prevent edema or hemorrhage, especially during several days after endarterctomy st...

BACKGROUND AND PURPOSE Individualizing mean arterial blood pressure targets to a patient's cerebral blood flow autoregulatory range might prevent brain ischemia for patients undergoing cardiopulmonary bypass (CPB). This study compares the accuracy of real-time cerebral blood flow autoregulation monitoring using near-infrared spectroscopy with that of transcranial Doppler. METHODS Sixty adult ...

Transcranial Doppler ultrasonography can map the changes in blood velocity that result from stenosis or occlusion of the middle cerebral artery. To evaluate patterns of collateral blood flow in disease of the middle cerebral artery stem, we used both cerebral angiography and transcranial Doppler ultrasonography to study the systolic blood velocities in both anterior cerebral arteries in 10 cons...

The dynamics of the cerebral vascular response to blood pressure changes in hypertensive humans is poorly understood. Because cerebral blood flow is dependent on adequate perfusion pressure, it is important to understand the effect of hypertension on the transfer of pressure to flow in the cerebrovascular system of elderly people. Therefore, we examined the effect of spontaneous and induced blo...

It has been shown that cerebral oxygen consumption and blood flow are normal and cerebral vascular resistance is increased in patients with essential hypertension (1). Clinicians have questioned the advisability of lowering arterial pressures in hypertensive patients because of the possible untoward effects consequent to decreased cerebral blood flow (2, 3). We have studied the effect of hypote...