Between May 2. 1990 and August 18. 1999. a total of 135 intestinal transplants were performed at our center. Of these. 18 (13%) were multiviseeraL which included stomach. duodenum. pancreas. and intestine. The liver was part of the graft in all but three cases and donor colon was included in 10 (56%). Nine were adults and 10 were females. Of the 18 grafts. 15 were primary. and the indications f...

Background: Systemic lupus erythematous (SLE) is a multisystemic and autoimmune inflammatory disease characterized by production of autoantibodies against different cellular components. We aimed to investigate children with SLE in terms of clinical symptoms and laboratory findings who referred to Lupus clinic.Materials and Methods: In this cross-sectional study, 36 children with SLE refer...

An intravenous (i.v.) formulation of mycophenolate mofetil (MMF; CellCept, Roche Pharmaceuticals, Inc., Palo Alto, CA) that will enable its administration to patients unable to tolerate oral medication is available. Two separate studies, an open-labeled pharmacokinetic (PK) study and a double-blind safety study, were performed. Within 24 h after transplant, 153 (safety study) and 45 (PK study) ...

WHAT IS YOUR DIAGNOSIS? A 54 year-old diabetic man, who had received a renal transplant two years ago due to diabetic nephropathy, was referred to our center. The allograft had a good function and creatinine level was normal. He was febrile since 2 months ago and had non-productive cough. He was admitted and evaluated in another center. No abnormality was found in his chest x-ray at that time a...

Report of a Case. A 37-year-old Nigerian man with a 14year history of bilateral Mooren ulceration had a right corneal perforation and a desmetocele in his severely damaged left eye (Figure, A and B). Snellen visual acuity was 6/60 OD, improving to 6/36 OD with pinhole, and hand movements OS. Systemic cyclosporine at a dosage of 5 mg/kg/d and prednisolone tapering from 1 mg/kg/d and ceasing afte...

TOPIC: Lung Cancer TYPE: Medical Student/Resident Case Reports INTRODUCTION: Chronic cough is one of the most common symptoms for which outpatient care sought. The differential diagnosis broad, and many patients undergo extensive evaluation. We here report a rare case chronic with progressive dyspnea due to Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia( DIPNECH), followed by brie...

Mycophenolic acid (MPA) is a relatively new immunosuppressive drug, used since the nineties for the prevention of rejection in kidney transplantation. MPA has not only proved effective in preventing rejection, being even superior to azathioprine, but also seems to cause less adverse effects than other immunosuppressive drugs [1]. Because of these favourable experiences with MPA in renal transpl...

M ycophenolic acid (MPA)-based therapies are widely used in combination with calcineurin inhibitors as maintenance immunosuppression for kidney transplant recipients (1). The two MPA therapies used in clinical transplantation are mycophenolate mofetil (MMF [brand name CellCept, Roche Pharmaceuticals, Nutley, NJ]) and mycophenolate sodium (MPS [brand name Myfortic, Norvartis Pharmaceuticals, Nut...

BACKGROUND Immune thrombocytopenic purpura (ITP) is primarily characterized by immune-mediated destruction of platelets in circulation. Major treatment options range from careful observation, steroids, immunosuppressive medications, immunoglobulins to splenectomy. Interestingly and rarely, ITP has also been reported after solid organ transplantation in patients receiving immunosuppressive medic...

Since the introduction of coronary angioplasty, every advance has been shadowed by the phenomenon known as «restenosis». Attempts to avoid the vascular reaction naturally generated by «mother nature» in response to the vascular damage induced by catheterization have either failed or had only limited success. Nevertheless, the findings of the recently published RAVEL study seem to indicate that ...