Primary cutaneous lymphomas have a distinct clinical behavior and prognosis, and therefore require a different therapeutic approach, as compared with their primary nodal equivalents. The European Organization for Research and Treatment of Cancer (EORTC) classification for primary cutaneous lymphomas recognizes a limited number of cutaneous T-cell lymphomas and cutaneous B-cell lymphomas and is ...

correct diagnosis and classification of lymphoid neoplasms depends on the integration of morphologic, immunophenotypic and molecular genetic features. the mature small b cell lymphomas despite their overlapping histomorphologies, have different clinical behavior and treatment. in this review, differential diagnosis of this category of tumors and a practical approach based on biomarkers evaluati...

BACKGROUND Natural killer and natural killer-like T-cell lymphomas presenting in the skin usually demonstrate aggressive behavior, an angiocentric distribution and a characteristic immunophenotype. In contrast, primary cutaneous CD30+ lymphoproliferative disorders form a heterogeneous spectrum including anaplastic large cell lymphomas, the majority of which display a good prognosis. Lymphomas w...

Abstract T-cell lymphomas are rare neoplasms that have complex pathology. The multiparameter approach has been recommended by World Health Organization (WHO) for the classification of taking into account morphology, immunophenotype, genetics, and clinical features. This also includes division established on possible cell-of-origin (COO) from T regulatory or T-follicular helper (TFH) cells. rece...

Secondary lung infiltration by lymphomas occurs frequently. To our knowledge, however, no recent studies have attempted to discriminate histologic patterns of lung infiltration in the lymphoma subtypes. We retrospectively evaluated the frequency of lung infiltration and the respective infiltration patterns by lymphomas at autopsy, during an 11-year period. Lymphomas were classified according to...

We analyzed the susceptibility of 10 AKXD recombinant inbred (RI) mouse strains to lymphomas. These strains were derived from crosses of AKR/J, a highly lymphomatous strain, and DBA/2J, a weakly lymphomatous strain. Of the 10 strains analyzed, nine showed a high incidence of lymphoma development. As with the other 13 AKXD strains analyzed previously (M. L. Mucenski, B. A. Taylor, N. A. Jenkins,...

Lymphomas are classified as Hodgkin’s and Non-Hodgkin’s lymphomas (HL NHL) NHL being further sub-divided into B, T and Null cell categories on the basis of WHO classification. With a few exceptions worldwide, B-NHL are more common, accounting approximately 80-85% of all cases of NHL compared to T-NHL, which accounts for about 10-15% of all NHL cases. The incidence of NHL has shown a steady incr...

The non-Hodgkin's lymphomas are a heterogeneous group of diseases. Cell marker studies over the past 10-15 years have demonstrated that majority adult B cell lymphocyte origin while minority T origin. They vary in their prognosis according to histologic and clinical features.

After infections, malignancies, lymphomas especially, are the second most frequent cause of death in patients with inborn errors immunity. Factors predetermining appearance and aggressiveness include gene defects, defects immune surveillance regulation as well infections oncogenic viruses. Aggressive non-Hodgkin lymphomas, mostly diffuse large B-cell Bukit subtypes predominant deoxyribonucleic ...