background: the metabolically active tumor cells may be characterized by a pronounced adenosine release that regulates the growth and development of the tumor. consequently, the expression pattern of defined receptor subtypes will be an important determinant for specific effects of adenosine on the control of tumor cell growth. in recent studies, the expression profile, signal transduction, mol...

primary de novo intraosseous carcinoma is a rare neoplastic lesion which commonly occurs in the jaws. it is an epithelial odontogenic malignancy arising from odontogenic epithelial residues in the bone rather than from a preexisting epithelial lesion. in the present case report, the clinical, radiological and histological features of primary de novo intraosseous carcinoma are discussed and its ...

papillary thyroid carcinoma (ptc) is one of the most commonly diagnosed types of differentiated carcinoma of the thyroid. it is stated that lung is the most common site of metastasis followed by bone. the incidence of paranasal sinus (pns) metastasis is fairly uncommon in case of thyroid carcinoma. to the best of our knowledge, no case of metastatic ptc to nasal cavity has been reported. in thi...

Neuroendocrine tumor of the lung is classified into four subtypes according to the recent World Health Organization Classification: typical carcinoid, atypical carcinoid, small cell carcinoma, and large cell neuroendocrine carcinoma (LCNEC) [1]. LCNEC is a relatively rare histopathological subtype of lung carcinoma, which accounts for approximately 3% of all lung carcinomas [1]. It has been wel...

Polo-like kinase 1 (PLK1) has been suggested to serve as oncogene in most human cancers. The aim of our study is to present more evidence about the clinical and prognostic value of PLK1 in lung squamous cell carcinoma patients. The status of PLK1 was observed in lung adenocarcinoma, lung squamous cell carcinoma and normal lung tissues through analyzing microarray data set (GEO accession number:...

Introduction: Cytological evaluation is an important, usually initial diagnostic modality in patients with suspected malignant lung masses. Bronchoscopic washing, bronchoalveolar lavage, bronchial brushing and fine needle aspirations may complement tissue biopsies the diagnosis of cancer. This study was undertaken to compare efficacy wash cytology correlate it histopathology cases cancer at a t...

There are some reports on the lignan constituents of Linum spp. In this study, we investigated the cyototoxicity of Linum spp. in vitro cultures for the first time. If they show significant cytotoxic activity, they will be valuable candidates for isolation of cytotoxic compounds in large scale from them by tissue culture technology. In our study, we chose normal root, hairy root and calli cultu...

Abstract Background Small-cell carcinoma (SMCC) of hypopharynx is an extreme rare entity in the head and neck region. It commonly arising from pulmonary origin. We report a case small-cell that caused upper airway obstruction elderly gentleman. Case presentation A 67-year-old man presented to otorhinolaryngology clinic with 4-month history worsening shortness breath stridor. He was heavy tobacc...

Correlation between the expression of STK33 and the pathology of lung cancer was investigated, to explore its effects on prognosis. Hundred and two lung cancer patients diagnosed by pathological examinations were randomly selected in Shanghai Jiao Tong University Affiliated Sixth People's Hospital from February, 2012 to February, 2017 to serve as observation group, and the tumor tissues were co...

In this study, we examined the expression of glypican-3 (GPC3) in the 2 most common histological types of lung cancer, squamous cell carcinoma and adenocarcinoma, and explored the relationship between GPC3 expression and the prognosis of these 2 types of lung cancers. Lung cancer tissues and paracancerous tissues were collected from a total of 60 patients with lung squamous cell carcinoma or lu...