نتایج جستجو برای: cell line model

تعداد نتایج: 3813831  

Journal: :فصلنامه علمی پژوهشی گیاهان دارویی 0
n rahimifard department of microbiology, food and drug laboratory research center (fdlrc), moh & me h hajimehdipoor traditional medicine and materia medica research center and department of traditional pharmacy, school of traditional medicine, shahid beheshti university of medical sciences, tehran, iran tel & fax: +98 – 21 - 88776027 mh hedayati department of biotechnology, pasture institute of iran o bagheri molecular biotechnology research center, baqiatalah university of medical sciences h pishehvar department of microbiology, pharmaceutical sciences branch, islamic azad university y ajani department of pharmacognosy and pharmaceutics, institute of medicinal plants, acecr

background: mentha species are widely used in traditional medicine mostly as anti-flatulence. nowadays, their usage as flavor and preservative in food, cosmetic and pharmaceutical industries has been developed. moreover, cytotoxic effects of some mentha species have been reported. objective: in this study, cytotoxic properties of mentha piperita, m. spicata, m. aquatica, m. crispa, m. pulegium ...

Journal: :iranian journal of public health 0
mansoor aletaha behzad mansoori ali mohammadi mehdi fazeli behzad baradaran

background: breast cancer is the most common diagnosed cancer among women in the world. snail1 plays a role in the development of the invasive phenotypes of cancer, neural cell differentiation, cell division and apoptosis in tumor cells. traces of snail1 in metastasis of breast cancer to bone are observed. the aim of this study was to investigate the effect of specific snail1 sirnas on the prol...

Journal: :iranian journal of basic medical sciences 0
mahdi mojarrab pharmaceutical sciences research center, school of pharmacy, kermanshah university of medical sciences, kermanshah, iran sajjad nasseri students research committee, kermanshah university of medical sciences, kermanshah, iran leila hosseinzadeh pharmaceutical sciences research center, school of pharmacy, kermanshah university of medical sciences, kermanshah, iran farah farahani pharmaceutical sciences research center, school of pharmacy, kermanshah university of medical sciences, kermanshah, iran

objective(s): in the current study antioxidant capacities of five different extracts of artemisia ciniformis aerial parts were evaluated by cell-free methods. then seven fractions of the potent extract were selected and their antioxidant capacity was assayed by cell free and cell based methods. materials andmethods: antioxidant ability was measured using the: 2, 2-diphenyl-1-picrylhydrazyl (dpp...

Journal: :iranian journal of toxicology 0
ندا مهدی نژادگرجی neda mahdinezhadgorji msc. fatemeh zahra infertility and reproductive health research center, babol university of medical sciences, babol, iran. سیدغلام علی جورسرایی seyed gholam ali jorsaraei department of anatomy and embryology, fatemeh zahra infertility and reproductive health research center, babol university of medical sciences, babol, iran ویدا حجتی vida hojati . departmeant of biology,college of biological sciences,damghan branch,islamic azad universitiy,damghan, iran. ابراهیم ذبیحی ebrahim zabihi departmeant of cellular and molecular biology, babol university of medical science, babol, iran آسیه خلیلپور asieh khalilpour departmeant of cellular and molecular biology, babol university of medical science, babol, iran زینب عابدین zainab abedian departmeant of cellular and molecular biology, babol university of medical science, babol, iran عیسی طهماسب پور

background:gossypol is a yellow toxic pigment from the cottonseed that can cause acute or chronic toxicity in humans and animals by affecting the testicular tissues. nowadays cottonseed is used as food supplement for ruminants specially the sheep. in this study, two different stem cell lines of testicular tissue including gc1-spg (mouse testis) and sftf-pi43 (sheep testis) cells were used to ev...

Journal: :international journal of preventive medicine 0
shabnam nadjafi soltan-ahmad ebrahimi nahid rahbar-roshandel

background: oligodendrocytes, the myelinating glial cells of central nervous system, are highly vulnerable to ischemic‑induced excitotoxic insult, a phenomenon in which calcium overload triggers cell death. berberine is an alkaloid extracted from medicinal herbs as coptidis rhizoma with several pharmacological effects like inhibition of neuronal apoptosis in cerebral ischemia. methods: we exami...

Journal: :research in pharmaceutical sciences 0
somayeh atari-hajipirloo 1department of biochemistry , student research committee,urmia university of medical sciences, urmia, i.r. iran. saba nikanfar 2department of biochemistry, urmia university of medical sciences, urmia, i.r. iran. amir heydari 3department of pharmacology, cellular and molecular research center, urmia university of medical sciences, urmia, i.r. iran. fatemeh kheradmand 4department of clinicalbiochemistry, cellular and molecular and solid tumor research center, urmia university of medical sciences, urmia, i.r. iran.

mono-targeting by imatinib as a main antitumor agent does not always accomplish complete cancer suppression. 2,5-dimethyl-celecoxib (dmc) is a close structural analog of the selective cyclooxygenase-2 (cox-2) inhibitor, celecoxib, that lacks cox-2 inhibitory function. in this study, we aimed to show the apoptotic effects of imatinib in combination with dmc in human ht-29 colorectal cancer (crc)...

Journal: :iranian journal of radiation research 0
s.m.j. mortazavi department of medical physics and medical engineering , school of medicine, shiraz university of medical sciences, shiraz, iran n. erfani shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz, iran h. mozdarani department of medical genetics, faculty of medical sciences, tarbiat modares university, tehran, iran r. azmoonfar radiology department, school of paramedical sciences, shiraz university of medical sciences, shiraz, iran n. shokrpour school of paramedical sciences, shiraz university of medical sciences, shiraz, iran

background: radiation-induced bystander effect is a response which results in damage in non-irradiated cells in response to signals from the irradiated cells. the aim of the present study was to investigate microwave-induced bystander effect from a gsm mobile phone simulator on induction of apoptosis in jurkat cell line. materials and methods: jurkat cells were divided into three groups of non-...

Journal: :basic and clinical neuroscience 0
sareh kazmi laya kafami ahmad ebrahimi behnam jameie mohammad taghi joghataiee

introduction: oxidative stress and neuroinflammation are involved in neurodegeneration procedure in parkinson’s disease. recently, neuroprotective potential of boswellia resin has been demonstrated. therefore, this study examined whether administration of boswellia resin would attenuate mpp+- induced neuronal death in sk-n-sh- cell line, a human dopaminergic neurons- in vitro. methods: boswelli...

Journal: :iranian journal of pharmaceutical research 0
marzieh amirmostofian 1department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran/iran farzad kobarfard department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran/iran hamed reyhanfard department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran/iran vida mashayekhi department of pharmaceutical biotechnology, school of pharmacy, zanjan university of medical sciences, zanjan/ iran afshin zarghi shahid beheshti univ. med. sci.

a new series of 1,2-diaryl-4,5,6,7-tetrahydro-1h-benzo[d]imidazoles, possessing trimethoxy phenyl pharmacophore, were synthesized to evaluate their biological activities as tubulin inhibitors. cytotoxic activity of the synthesized compounds 7a-f was assessed against several human cancer cell lines, including mcf-7 (breast cancer cell), hepg2 (liver hepatocellular cells), a549 (adenocarcinomic h...

Journal: :iranian journal of pharmaceutical research 0
firouz faedmaleki faculty of veterinary medicine, islamic azad university - science and research branch, tehran, iran farshad h shirazi pharmaceutical sciences research center, shahid beheshti university of medical sciences, tehran, iran amir salarian deptartment of toxico-pharmacology, faculty of pharmacy, shahid beheshti medical university, tehran, iran hamidreza ahmadi ashtiani department of biochemistry and nutrition, zanjan university of medical sciences, iran islamic azad university, pharmaceutical seines branch, tehran, iran. hossein rastegar department of basic science, science and research branch, islamic azad university, tehran, iran.

nano-silver (agnp) has biological properties which are significant for consumer products, food technology, textiles and medical applications (e.g. wound care products, implantable medical devices, in diagnosis, drug delivery, and imaging). for their antibacterial activity, silver nanoparticles are largely used in various commercially available products. thus, the use of nano-silver is becoming ...

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