conclusions the patient underwent surgery applying a midline incision. the left kidney showed a lump pattern embedded in lower pole of the right kidney. left sided nephrectomy was performed while temporary right renal artery was clamped temporarily. histopathological evaluation revealed clear cell carcinoma with severe nuclear atypia (fuhrman grade 4/4). however, local recurrence was not detect...

background and aims: p504s (amacr) is a mitochondrial enzyme expressed in renal cell carcinoma. some of immunohistochemical markers in renal cell tumors are independent prognostic factor and show relation with histologic grading. amacr expression increases with higher histological grading in different tumors; however, in rcc it is not obvious. in this study, we tried to investigate if any relat...

diaphragmatic hernia, secondary to transhiatal esophagectomy, appears to be a relatively infrequent diagnosis. patients may be asymptomatic or present with various symptoms. diagnosis of this condition requires a high index of suspicion. the most common cause of diaphragmatic hernia is widened esophageal hiatus during surgery; therefore, narrowing the hiatus can prevent conduit herniation. here...

objective: systemic sclerosis (ss) is a chronic autoimmune disease of connective tissue, which involves skin and internal organs, and results in collagen deposition and fibroblasts activation. studies have reported a higher risk of malignancy in patients with progressive systemic sclerosis (pss).the aim of this study is to report a case of tongue squamous cell carcinoma (scc) in a patient with ...

a 2-year-old male hamster was presented because of left facial swelling and salivation. necropsy wasperformed and affected cheek pouch with tissue samples of regional and internal organs were submitted forhistopathological study. in histopathological examination it was found that the tumor consisted of cords andislands of tumoric epithelial cells which were diffused in the dermis. vacoulation o...

objective(s): the ability to measure cellular proliferation non-invasively in renal cell carcinoma may allow prediction of tumour aggressiveness and response to therapy. the aim of this study was to evaluate the uptake of 18ffluorothymidine (flt) pet in renal cell carcinoma (rcc), and to compare this to 18f-fluorodeoxyglucose (fdg), and to an immunohistochemical measure of cellular proliferatio...

intussusception is common cause of bowel obstruction in the paediatric age group compared to the elderly population. many times, the diagnosis may be difficult because of asymptomatic nature of this bowel disorder. we hereby describe the case of a 75-year-old male who presented with lethargy, weakness, loss of movement in the joints and was found to be anemic. the haemoglobin level was low so h...

head and neck squamous cell carcinoma, including oral squamous cell carcinoma (oscc) is the sixth most common cancer in the human population. despite significant efforts committed in treatment of oscc the overall survival rate of oscc has not improved significantly. activating mutations in the fibroblast growth factor receptor 3 (fgfr3) genes are responsible for some human cancers, including bl...

purpose: to report a case of isolated corneal squamous cell intraepithelial neoplasia in a patient with unilateral dry eye symptoms. case report: a 48 year old man presented with history of thermal corneal injury in his left eye two years ago, with decreased visual acuity and dry eye symptoms a short time thereafter. he was treated for dry eye with no improvement in symptoms. upon presentation,...