background celiac disease occurs primarily in whites of northern european ancestry. previous beliefs about epidemiology of celiac disease in iran has changed after recent studies on the disease. the aim of this study is to find the frequency of celiac disease among patients with irritable bowel syndrome. materials and methods during one-year period (2006-07), patients with irritable bowel syndr...

multiple sclerosis (ms) is an autoimmune inflammatory process that affects the central nervous system (cns). celiac disease (cd) is a systemic autoimmune disorder of gluten intolerance. based on the presumed association of ms with multiple autoimmune processes, the coincidence of ms with gluten sensitivity has been investigated with controversial results. here, we report a known case of ms with...

background: celiac disease (cd) may be misdiagnosed as irritable bowel syndrome (ibs) resulting in long delays in diagnosing cd. there are contradictory reports on the association of cd with ibs.appropriateness of screening all patients with ibs for cd and how to screen them are still under question. materials and methods: in a cross-sectional study, 328 ibs patients (rome ii) referred to the p...

background: the most common neurologic manifestation of gluten sensitivity is ataxia, which accounts for up to 40% of idiopathic sporadic ataxia. timing of diagnosis of gluten ataxia is vital as it is one of the very few treatable causes of sporadic ataxia and causes irreversible loss of purkinje cells. antigliadin antibody (aga) of the igg type is the best marker for neurological manifestation...

gluten associated disorders and the question around these associations has recently attracted attentions of many health professionals. this is because of high prevalence of undiagnosed gluten related disorders presenting with a multitude of symptoms and complications inside and outside small bowel. while the environmental factors associated with a complex genetics are leading to destructions of...

Introduction: Gluten is a protein found in grains.  Research has shown that the gluten that is in grains of wheat, barley, rye, and oats (to a lesser degree) is toxic to many individuals.  While gluten is essential for the make-up of these 4 grains, our bodies do not need it. Is it healthful?  The protein in today’s wheat is poorly digested and can be harmful.  An estimated 95% of prepared fo...

background: coeliac disease (cd) is characterized by malabsorption resulting from inflammatory injury to the mucosa of the small intestine by an inappropriate immune response to dietary gluten proteins. the aim of this study was to assess the prevalence of cd in our endoscopy unit by taking routine duodenal biopsies during upper gi endoscopy. materials andmethods: nine hundred and thirteen pati...

ganglioneuroma is a very rare cause of chronic diarrhea in children. this benign tumor usually presents with diarrhea and failure to thrive. it is necessary for physicians to be familiar with this rare cause of chronic diarrhea. here we present and discuss such a case.

background celiac disease is an autoimmune mediated small intestine inflammation which is occurred due to hypersensitivity reaction to gluten and related proteins in diet in genetically predisposing individuals. prevalence of celiac among the population is about 0.5 – 1 % in most countries. frequency of celiac disease in children is a subject of few research .in this study, we aim to determine ...

background and objective: celiac disease is an autoimmune disorder, characterized by inflammation, villous atrophy, and crypt hyperplasia of the small bowel mucosa. in this study we considered and compared sensitivity and specificity of serological tests in patients with celiac disease. materials and methods: in this cross-sectional study we prospectively recruited children with suspected celia...