With the objective of reducing the high incidence of iron deficiency anemia, the Brazilian National Health Surveillance Agency (ANVISA) adopted Resolution 344 in December 2002, which made the addition of iron and folic acid to all industrialized wheat and maize flours in Brazil compulsory. After a series of doubts about this universal measure of food fortification, a review of case reports on l...

BACKGROUND Methotrexate (MTX) is the most commonly used disease-modifying drug in the treatment of rheumatoid arthritis (RA); however, it causes many side effects, including pulmonary lesions. In this review, we characterised the histopathological features of MTX-induced pulmonary lesions in RA patients. AIM We carried out an electronic search of the relevant literature published during the p...

Journal of Orthopaedic Case reports was started in 2011 and is in its fourth year of publication. The journal was started due to certain issues that we were facing at that time with regards to publication of case reports. Most Journals had stopped accepting case reports (as they affect the impact factor negatively) and other accepted it in very limited numbers [1]. There was no other avenue at ...

abstract renal medullary carcinoma (rmc) is an uncommon aggressive neoplasm of the kidney. rmc is biologically aggressive with a very poor prognosis, and metastasis is seen in up to 95% of the patients at diagnosis or shortly thereafter. the common sites of metastasis are respectively lymph nodes, lungs, livers, and adrenal glands in order of frequency. the presence of poorly differentiated eos...

introduction vincent’s angina refers to acute necrotizing ulcerative lesions of the oral mucosal membranes and tonsils. case presentation; in this case, we report a 17-year old girl with emotional stress referred with symptoms of vincent’s angina. gram staining showed numerous fusospirochetal bacteria. with antibiotic therapy, amoxicillin and cephalexin, no clinical improvement was observed but...

Case report is the oldest and the best-known type of publication in medicine. Many original observations, recognition of new diseases, novel diagnostic and therapeutic methods, unusual forms of common diseases, and complications were first published as case reports. Case reports have become a standard and indispensable part of the medical literature. However, getting a case report published in ...

cemento-ossifying fibroma is a fibro-osseous lesion that has benign neoplastic behavior. we report two cases of cemento-ossifying fibroma (cof) and review the literature in order to study the imaging findings of cof. it is almost unavoidable that diagnosis of fibrous dysplasia from cof will be complicated by the fact that some pathologic features are shared by both lesions. so the final definit...