casapase 3 activity

Susan J. Lindsay Yaobo Xu Steven N. Lisgo Lauren F. Harkin Andrew J. Copp Dianne Gerrelli Gavin J. Clowry Aysha Talbot Michael J. Keogh Jonathan Coxhead Mauro Santibanez-Koref Patrick F. Chinnery

Citation: Lindsay SJ, Xu Y, Lisgo SN, Harkin LF, Copp AJ, Gerrelli D, Clowry GJ, Talbot A, Keogh MJ, Coxhead J, Santibanez-Koref M and Chinnery PF (2016) HDBR Expression: A Unique Resource for Global and Individual Gene Expression Studies during Early Human Brain Development. Front. Neuroanat. 10:86. doi: 10.3389/fnana.2016.00086 HDBR Expression: A Unique Resource for Global and Individual Gene...

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Raf-1 activation disrupts its binding to keratins during cell stress

Journal: :The Journal of Cell Biology 2004

Nam-On Ku Haian Fu M. Bishr Omary

Keratins 8 and 18 (K8/18) heteropolymers may regulate cell signaling via the known K18 association with 14-3-3 proteins and 14-3-3 association with Raf-1 kinase. We characterized Raf-keratin-14-3-3 associations and show that Raf associates directly with K8, independent of Raf kinase activity or Ras-Raf interaction, and that K18 is a Raf physiologic substrate. Raf activation during oxidative and...

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