Introduction: The development of a self-limiting caries removal technique would be of great clinical importance. Smart bur II is a relatively new bur in the dental market and its manufacturer is claiming that it is the ultimate bur for selective caries removal. Objectives: The aim of this study was to evaluate caries removal time and efficacy of Smart bur II in comparison with conventional carb...

Dental caries is the most common oral disease seen in children and adolescents. This study was conducted to assess prevalence of dental caries at different water fluoride levels in Nalgonda district of Andhra Pradesh. A total of 1800 school children aged 12-15 years were selected by stratified cluster sampling from three areas with different levels of natural fluoride concentrations in drinking...

Dental caries (tooth decay) is an infectious disease. Its etiology is not fully understood from the microbiological perspective. This study characterizes the diversity of microbial flora in the saliva of children with and without dental caries. Children (3-4 years old) with caries (n = 20) and without caries (n = 20) were recruited. Unstimulated saliva (2 mL) was collected from each child and t...

Recent evidence suggests that genetic studies may contribute to a better understanding of individual susceptibility to caries. Matrix metalloproteinases (MMPs) and their tissue inhibitors have been suggested to be involved in the caries process. The purpose of this study was to determine if polymorphisms in MMP2 (rs243865), MMP9 (rs17576), MMP13 (rs2252070), and TIMP2 (rs7501477) were associate...

Studies indicate that previous caries experience can influence future caries development; however, caries-free individuals also may develop caries. The aim of this study was to examine the relationship between baseline caries experience and salivary mutans streptococci (SMS) levels as an indicator for predicting caries incidence in pre-school children. One hundred forty-eight preschool children...

Dental caries is an infectious disease which still constitutes a public health concern. It begins at an early age and is caused mainly Streptococcus mutans (S. mutans). The aim of this study was to characterize the salivary humor immune response to S. mutans proteins in patients with caries, with history of caries and without caries, in order to determine which S. mutans proteins participate in...

Dental caries results from altered microbial community activity in disease compared to health. Caries advanced into dentin was compared with coronal caries and caries-free sites. Oral bacterial samples were obtained from young children, placed in RNAlater and stored frozen. mRNAwas purified and sequenced on an Illumina NextSeq 500 platform. Gene sequences were aligned against taxa in HOMD and g...

The advent of "Adhesive Dentistry" has simplified the guidelines for cavity preparation enormously. The design and extent of the current preparations are basically defined by the extent and shape of the caries lesion, potentially slightly extended by bevelling the cavity margins in order to meet the modern concept of minimally invasive dentistry. New caries excavation techniques have been intro...

Available evidence indicates that infants, for the most part, acquire their oral flora, in particular Streptococcus mutans, from their mothers. The purpose of this study was to explore the effect of rampant caries in rat dams on subsequent caries activity in their offspring. Rampant caries was induced by surgical desalivation of four dams, and subsequent infection with Streptococcus sobrinus 67...

BACKGROUND Candida albicans may have cariogenic potential but its role in caries etiology has not been established. The aim of this study was to determine candida albicans in supragingival dental plaque and infected dentine of cervical and proximal in early childhood caries (ECC). METHODS This cross-sectional study was carried out on 6o children aged 2-5 years, which were divided into 3 group...