BACKGROUND The aim of this study was to determine the association of dental caries and BMI-for-age in preschool children and whether BMI-for-age is similar or different between Severe Early Childhood Caries (S-ECC) and caries free children. MATERIALS AND METHODS Four hundred preschool children aged 30-70 months were entered into this study. The parameters examined in this study were weight, h...

The ecological plaque hypothesis for the aetiopathogenesis of caries implies a microbial shift towards a more acidogenic and aciduric dental plaque microflora, due to a frequent carbohydrate intake. Certain plaque bacteria exhibit metabolic activity, at a low pH. A correlation exists between the increased numbers of some aciduric bacterial species, e.g. mutans streptococci and lactobacilli, and...

AIMS The aim of this study was to estimate the count of Streptococcus mutans in saliva of caries free children using Dentocult SM strip mutans and to evaluate the effect of fluoride varnish on the Streptococcus mutans count in saliva of these caries free children. METHODS AND MATERIAL Thirty caries free children were selected for the study based on the information obtained from a questionnair...

Early childhood caries affects 28% of children aged 2-6 in the US and is not decreasing. There is a well-recognized need to identify susceptible children at birth. Caries-free adults neutralize bacterial acids in dental biofilms better than adults with severe caries. Saliva contains acidic and basic proline-rich proteins (PRPs) which attach to oral streptococci. The PRPs are encoded within a sm...

BACKGROUND This study's aim was to compare the dental biofilm metabolite-profile of caries-active (N=11) or caries-free (N=4) children by gas chromatography-mass spectrometry (GC/MS) analyses. METHODS Samples collected after overnight fasting, with or without a previous glucose rinse, were combined for each child based on the caries status of the site, re-suspended in ethanol and analyzed by ...

BACKGROUND The multiple functions of saliva play a significant role in the prevention of dental caries. METHODS Chewing gum is known to stimulate salivary flow, and the results of studies of the role of stimulated saliva in the oral clearance of food particles, neutralization of dental plaque acids and reduction of the incidence of dental caries have been reported. The author reviews the resu...

BACKGROUND Despite the decline in childhood caries prevalence, seen particularly in 1980s, in recent years there have been reports that the declining trend has stopped or even reversed in some countries. The aim of the study was to analyse data from previous epidemiological studies on early childhood caries in the Czech Republic, conduct a secondary analysis of trend in dental caries prevalence...

OBJECTIVE Early childhood caries (ECC) has become a prevalent public health problem among Chinese preschool children. The bacterial microflora is considered to be an important factor in the formation and progress of dental caries. However, high-throughput and large-scale studies of the primary dentition are lacking. The present study aimed to compare oral microbial profiles between children wit...

Recently, high-throughput sequencing has improved the understanding of the microbiological etiology of caries, but the characteristics of the microbial community structure in the human oral cavity with and without caries are not completely clear. To better understand these characteristics, Illumina MiSeq high-throughput sequencing was utilized to analyze 20 salivary samples (10 caries-free and ...