The absence of clinical response in 30% to 40% of patients receiving cardiac resynchronization therapy (CRT) poses a great challenge to heart failure clinicians and device implanters. It is well documented that positioning of the left ventricular (LV) lead in areas of myocardial scar in patients with ischemic cardiomyopathy is associated with a diminished response to CRT. Regions of slow conduc...

The following articles are being highlighted as part of Circulation: Cardiovascular Imaging’s Topic Review. This series will summarize the most important manuscripts, as selected by the editors, that have been published in the Circulation portfolio. The studies included in this article represent the most significant research in the area of congenital heart disease. (Circ Cardiovasc Imaging. 201...

The following are highlights from the new series, Circulation: Cardiovascular Imaging Topic Review. This series summarizes the most important articles, as selected by the editors, that have been published in the Circulation portfolio. The objective of this new series is to provide our readership with a timely, comprehensive selection of important articles that are relevant to the imaging and ge...

Uncorrected chronic ischemic mitral regurgitation (CIMR) is associated with decreased left ventricular (LV) torsion and may contribute to a vicious cycle wherein “MR begets MR.” It has not been definitively established, however, whether the reduced LV torsion in CIMR is a direct result of the infarct, the MR, or a combination of the two. Currently, the most common technique to restore valve com...

Molecular imaging has the potential to profoundly impact preclinical research and future clinical cardiovascular care. In Part I of this 2-part consensus article on multimodality cardiovascular molecular imaging, the imaging methodology, evolving imaging technology, and development of novel targeted molecular probes relevant to the developing field of cardiovascular molecular imaging were revie...

The following are highlights from the new series, Circulation: Cardiovascular Imaging Topic Review. This series summarizes the most important articles, as selected by the editors, that have been published in the Circulation portfolio. The objective of this new series is to provide our readership with a timely, comprehensive selection of important articles that are relevant to the imaging and ge...

There has been a shift in emphasis from treatment of disease to the primary or secondary prevention of disease, primarily to advance human health through preservation of quality of life and improvement in survival, but also in part to control the escalating costs of health care. The prevention of disease necessitates early detection and risk stratification before the manifestation of disease, w...

The following are highlights from the new series, Circulation: Cardiovascular Imaging Topic Review. This series summarizes the most important articles, as selected by the editors, that have been published in the Circulation portfolio. The objective of this new series is to provide our readership with a timely, comprehensive selection of important articles that are relevant to the imaging and ge...

Uncorrected chronic ischemic mitral regurgitation (CIMR) is associated with decreased left ventricular (LV) torsion and may contribute to a vicious cycle wherein “MR begets MR.” It has not been definitively established, however, whether the reduced LV torsion in CIMR is a direct result of the infarct, the MR, or a combination of the two. Currently, the most common technique to restore valve com...

The following articles are being highlighted as part of Circulation: Cardiovascular Imaging’s Topic Review. This series summarizes the most important articles, as selected by the editors, that have published in the Circulation portfolio. The studies included in this article represent the most significant research in the area of structural heart disease, cardiac function, aortic disease, and mol...