Adrenaline (epinephrine) has been used for cardiopulmonary resuscitation since 1896; the rationale behind its use is thought to be its α-adrenoceptor-mediated peripheral vasoconstriction, causing residual blood-flow to be diverted to coronary and cerebral circulations. This protects these tissues from ischaemic damage and increases the likelihood of restoration of spontaneous circulation. Clini...

Objective: To investigate the effect of intravascular heat exchange in saving the lives of patients after cardiopulmonary resuscitation. Methods: The clinical data of a female patient who was given cardiopulmonary resuscitation for 1.67 h in July 2014 in our hospital was retrospectively analyzed. An intravascular heat exchange procedure was performed on the patient to control her body temperatu...

BACKGROUND AND PURPOSE Cerebral blood flow during cardiopulmonary resuscitation is inadequate to meet cerebral metabolic demand. Adrenergic agonists improve cerebral blood flow, but clinical trials of increased doses in adults have not shown improved outcome from cardiac arrest. This may be due to adverse beta-agonist-mediated effects. The purpose of this study was to determine the effect of an...

INTRODUCTION Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion injury. It is unknown whether cardiac arrest also triggers the release of cerebral inflammatory molecules, and whether therapeutic hypothermia alters this inflammatory response. This study sought to examine whether hypo...

www.ccmjournal.org 243 Objective: To determine whether implementation of Composite Resuscitation Team Training is associated with improvement in survival to discharge and code team performance after pediatric in-hospital cardiopulmonary arrest. Design, Setting, and Subjects: We conducted a prospective observational study with historical controls at a 302-bed, quaternary care, academic children’...

PURPOSE OF REVIEW Despite a more widespread knowledge of basic cardiopulmonary resuscitation maneuvers in the community, the survival rate for patients with cardiac arrest has remained essentially unchanged in the past 30 years. Over the past few decades, many different compression-ventilation ratios have been studied in terms of best coronary and cerebral oxygen delivery, restoration of sponta...

Left atrial dissection (LatD) is a relatively rare perioperative complication during mitral valve repair. Here, we report a 64-year-old man who developed LatD after cardiopulmonary resuscitation was needed due to an extensive myocardial infarction. Aggressive cardiac massage resulted in cardiac rupture and massive bloody pleura effusion. Intraoperative three-dimensional transesophageal echocard...

conclusions the survival rate after in-hospital cpr was very low. the duration of cpr and the time of initiating cpr effects patients’ outcomes. these findings highlight the crucial role of an organized, skilled, well-established and timely cpr team. background despite several studies, there is no agreement on factors that affect survival after in-hospital cardiopulmonary resuscitation (cpr). o...