abstract background iron overload is the main transfusion related side effects in patients with transfusion dependent hemoglobinopathies. severe iron deposition in tissues leads to organ dysfunction. many organs can be affected such as heart, liver, and endocrine organs. cardiac failure and liver fibrosis are the consequent of iron overload in transfusion dependent hemoglobinopathy. magnetic re...

This paper presents flow results of a magnetic resonance imaging velocimetry system which relies on fluid motion estimation, and uses vorticity map differencing for calibrating its reliability. To validate this new concept, phase contrast magnetic resonance imaging on the right atrium of a healthy subject has been suggested. The study has demonstrated the state of change in blood flow patterns ...

OBJECTIVES In diabetes, extended adrenergic receptor stimulation with hyperglycemia and insulin deficiency is associated with cardiac autonomic dysfunction. Clinically evident diabetic cardiac autonomic neuropathy (CAN) is associated with a poor prognosis. Research studies indicate that autonomic function tests, which are traditionally used to diagnose diabetic CAN, are less sensitive than (123...

PURPOSE In many cardiac imaging applications, the accurate detection of the systolic and diastolic quiescent periods is critical in obtaining optimal image quality and is usually determined by observing cardiac motion in a CINE acquisition. This complicates the cardiac exam procedure and does not adapt to heart rate variations throughout the exam. In this study, we investigated the feasibility ...

Cardiomyopathy is a heterogeneous group of disorders of varying etiology. Heart failure from systolic and/or diastolic cardiac dysfunction is common to all. Certain disorders are distin‐ guished by life threatening arrhythmia. Onset of symptoms may be acute or progress from preclinical to symptomatic state over time and at a variable rate. Early recognition permits therapeutic intervention ther...

Introduction T2-weighted (T2w) cardiac MR imaging has established reputation as a sensitive technique to depict myocardial edema related to acute infarction. Together with delayed enhancement technique, T2w demonstrated valuable clinical potentials to differentiate acute damage from chronic infarction [1]. To minimize the myocardial signal loss caused by through-plane motion, T2w can be perform...

We aim to demonstrate the application of free-breathing prospectively gated carbon nanotube (CNT) micro-CT by evaluating a myocardial infarction model with a delayed contrast enhancement technique. Evaluation of murine cardiac models using micro-CT imaging has historically been limited by extreme imaging requirements. Newly-developed CNT-based x-ray sources offer precise temporal resolution, al...

The influence of physiological motion on magnetic resonance diffusion imaging techniques is studied. First, the applicability of the steady-state free precession (SSFP) imaging sequence for imaging of diffusion is studied with a novel, fast, and highly accurate computer simulation based on conditional random walk. By using measurements of in vivo brain motion, it is shown that the SSFP sequence...

A real-time interactive black-blood imaging system is described. Rapid blood suppression is achieved by exciting and dephasing slabs outside the imaging slice before each imaging excitation. Sharp-profiled radio frequency saturation pulses placed close to the imaging slice provide good blood suppression, even in views containing slow through-plane flow. In vivo results indicate that this techni...

OBJECTIVES The purpose of our study was to conduct an evidence-based evaluation of stress cardiac magnetic resonance imaging (MRI) in the diagnosis of coronary artery disease (CAD). BACKGROUND Stress cardiac MRI has recently emerged as a noninvasive method in the detection of CAD, with 2 main techniques in use: 1) perfusion imaging; and 2) stress-induced wall motion abnormalities imaging. M...