نتایج جستجو برای: cardiac conduction system disease

تعداد نتایج: 3736785  

Journal: :The Journal of clinical investigation 2016
Akshay Shekhar Xianming Lin Fang-Yu Liu Jie Zhang Huan Mo Lisa Bastarache Joshua C Denny Nancy J Cox Mario Delmar Dan M Roden Glenn I Fishman David S Park

Rapid impulse propagation in the heart is a defining property of pectinated atrial myocardium (PAM) and the ventricular conduction system (VCS) and is essential for maintaining normal cardiac rhythm and optimal cardiac output. Conduction defects in these tissues produce a disproportionate burden of arrhythmic disease and are major predictors of mortality in heart failure patients. Despite the c...

Journal: :Circulation research 2009
Carol Ann Remme Brendon P Scicluna Arie O Verkerk Ahmad S Amin Sandra van Brunschot Leander Beekman Vera H M Deneer Catherine Chevalier Fumitaka Oyama Haruko Miyazaki Nobuyuki Nukina Ronald Wilders Denis Escande Rémi Houlgatte Arthur A M Wilde Hanno L Tan Marieke W Veldkamp Jacques M T de Bakker Connie R Bezzina

Conduction slowing of the electric impulse that drives the heartbeat may evoke lethal cardiac arrhythmias. Mutations in SCN5A, which encodes the pore-forming cardiac sodium channel alpha subunit, are associated with familial arrhythmia syndromes based on conduction slowing. However, disease severity among mutation carriers is highly variable. We hypothesized that genetic modifiers underlie the ...

Journal: :The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 2006
Florence Rothenberg Igor R Efimov

The complete embryonic cardiac conduction system is difficult to view in three dimensions, primarily because there has not been a marker of all segments of the normal system throughout all stages of development. Imaging of the conduction system components within the atria has been particularly controversial because different markers reveal different pathways that may or may not represent conduc...

Journal: :European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 2006
Shun-ichiro Sakamoto Shigeo Yamauchi Hiromasa Yamashita Hajime Imura Yuji Maruyama Hidetsugu Ogasawara Nobuo Hatori Kazuo Shimizu

OBJECTIVE The atrial conduction properties associated with cardiac disease are speculated as the background of postoperative atrial fibrillation (POAF). We examined the atrial conduction patterns and conduction properties during sinus rhythm (SR) in patients that had undergone cardiac operations and evaluated the incidence of POAF in all patients. METHODS Fifty-two patients with stable SR who...

2009
Carol Ann Remme Brendon P. Scicluna Arie O. Verkerk Ahmad S. Amin Sandra van Brunschot Leander Beekman Vera H.M. Deneer Catherine Chevalier Fumitaka Oyama Haruko Miyazaki Nobuyuki Nukina Ronald Wilders Denis Escande Rémi Houlgatte Arthur A.M. Wilde Hanno L. Tan Marieke W. Veldkamp Jacques M.T. de Bakker Connie R. Bezzina

Conduction slowing of the electric impulse that drives the heartbeat may evoke lethal cardiac arrhythmias. Mutations in SCN5A, which encodes the pore-forming cardiac sodium channel subunit, are associated with familial arrhythmia syndromes based on conduction slowing. However, disease severity among mutation carriers is highly variable. We hypothesized that genetic modifiers underlie the variab...

Journal: :Rhode Island medical journal 2017
Lakir D Patel Jay S Schachne

Lyme disease is the most common tick-borne infection in the Northern hemisphere. Cardiac manifestations of Lyme disease typically include variable atrioventricular nodal block and rarely structural heart pathology. The incidence of Lyme carditis may be underestimated based on current reporting practices of confirmed cases. This case of a 59-year-old man with Lyme carditis demonstrates the uniqu...

2005
PAUL F. SCHELLHAMMER JACK W. C. HAGSTROM

The myocardium, all parts of the conduction system, and the S-A node contained iron in six patients with acquired iron-storage disease. The nerve fibers and ganglia contained negligible amounts. No correlation was demonstrated between the amount of histochemically demonstrated iron in the myocardium and conduction system, or the amount of transfused iron, or the amount of quantitatively analyze...

2004
Heather L. Bartlett Thomas D. Scholz Fred S. Lamb Daniel L. Weeks Lucille A. Carver

Bartlett, Heather L., Thomas D. Scholz, Fred S. Lamb, and Daniel L. Weeks.Characterization of embryonic cardiac pacemaker and atrioventricular conduction physiology in Xenopus laevis using noninvasive imaging. Am J Physiol Heart Circ Physiol 286: H2035– H2041, 2004; 10.1152/ajpheart.00807.2003.—Congenital heart defects often include altered conduction as well as morphological changes. Model org...

Journal: : 2021

A clinical case report of late diagnosis (in relation to manifestation) the classic phenotype Fabry disease in patient with cardiac involvement: phenocopy hypertrophy cardiomyopathy, arrhythmias and conduction abnormalities.

Journal: :Circulation 1967
P F Schellhammer M A Engle J W Hagstrom

The myocardium, all parts of the conduction system, and the S-A node contained iron in six patients with acquired iron-storage disease. The nerve fibers and ganglia contained negligible amounts. No correlation was demonstrated between the amount of histochemically demonstrated iron in the myocardium and conduction system, or the amount of transfused iron, or the amount of quantitatively analyze...

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