Objectives Cardiotoxicity is one of the major consequences in carbon monoxide poisoning. Following our previous work, in this study we aimed to define the myocardium changes induced by carbon monoxide (CO) intoxication and evaluate erythropoietin (EPO) effect on CO cardiotoxicity in rat. Materials and Methods Severe carbon monoxide toxicity induced by 3000 ppm CO in Wistar rat. EPO was admini...

The equilibria and kinetics of the reaction of the diheme proteins cytochrome cc’ derived from Rhodospirillum rubrum and Chromatium with carbon monoxide have been examined. There are wide differences in many respects. The pigment from Chromatium is half saturated by 0.2 pM CO, while that of R. rubrum requires a concentration of 400 PM. The kinetics of the combination reaction also differs. In s...

The magnetic properties of ColCu multilayers were investigated from 5 to 380 K and analyzed in terms of the interFace magnetism and mean-field model. The interface, which is about 1.2 w thick, is nonmagnetic at room temperature and becomes magnetic at 5 K with the average magnetization of 40% of the pure Co magnetization. The samples of X w Co/l0 A Cu behaved superparamagnetically as X ranged f...

Exposure of the photosynthetic bacterium Rhodospirillum rubrum to carbon monoxide led to increased carbon monoxide dehydrogenase and hydrogenase activities due to de novo protein synthesis of both enzymes. Two-dimensional gels of [35S]methionine-pulse-labeled cells showed that induction of CO dehydrogenase synthesis was rapidly initiated (less than 5 min upon exposure to CO) and was inhibited b...

The aim of the present study was to calculate reference equations for carbon monoxide and nitric oxide transfer, measured in two distinct populations. The transfer factor of the lung for nitric oxide (T(L,NO)) and carbon monoxide (T(L,CO)) were measured in 303 people aged 18-94 yrs. Measurements were similarly made in two distant cities, using the single-breath technique. Capillary lung volume ...

The potential of carbon monoxide to act as a therapeutic agent is now well-established. Controlled delivery of CO is best achieved using 'CORMs': molecules which release known amounts of carbon monoxide in response to a stimulus. Metal carbonyl complexes will release CO if irradiated with ultraviolet light, but it is only in the past five years that development of true 'photoCORMs' has been exp...

The report titled, “Technical Note 1834: Development of a Test Method to Determine Carbon Monoxide Emission Rates from Portable Generators,” presents a test method developed by the National Institute of Standards and Technology (NIST) for determining carbon monoxide (CO) emission rates from portable generators while operating in an enclosed space. NIST developed the test method under an interag...

Carbon monoxide at a concentration of 1000-2000 ppm was administered to sickle cell disease patients. In each of two patients, one 51Cr red cell survival study was carried out before CO administration, and a second study was initiated a few days before CO administration was started. In both, significant prolongation of red cell survival was observed, suggesting that the rheologic properties of ...

The management of carbon monoxide poisoning requires an accurate assessment of the extent of blood oxygenation. Measuring the fractional oxyhaemoglobin content by using co-oximetry gives a true picture of the oxygen-carrying capacity of blood in the presence of carboxyhaemoglobin. The use of readings from pulse oximetry or a standard blood gas analyser is insufficient and can be misleading. We ...