A preconditioned five-equation two-phase model coupled with an interface sharpening technique is introduced for simulation of a wide range of multiphase flows with both high and low Mach regimes. Harten-Lax-van Leer-Contact (HLLC) Riemann solver is implemented for solving the discretized equations while tangent of hyperbola for interface capturing (THINC) interface sharpening method is applied ...

deproteinisation with acetonitrile (along with methanol or other reagents) is a useful and rapid technique in analysis of drugs or their metabolites in human serum. in this paper application of this simple technique in biopharmaceutical analysis using capillary electrophoresis (ce) is evaluated. some drugs with different ionic and protein binding properties were selected and dissolved in human ...

Capillary electrophoresis (CE) with indirect UV detection is an interesting analytical method for the analysis of drugs and pharmaceuticals. Good and reproducible capillary quality is needed to develop robust methods and to facilitate method transfer in CE. It is widely accepted that preconditioning procedures are indispensable in capillary electrophoresis in order to achieve reproducibility of...

Capillary rarefaction occurs in many tissues in patients with essential hypertension and may contribute to an increased vascular resistance and impaired muscle metabolism. Rarefaction may be caused by a structural (anatomic) absence of capillaries, functional nonperfusion, or both. The aim of this study was to assess the extent of structural versus functional capillary rarefaction in the skin o...

Capillary Wetting of Colloidal Monolayers In article number 2208402, Shin-Hyun Kim and co-workers study capillary wetting colloidal monolayers by a limited volume molten polymer, which enables the production complex wavy surfaces with controlled waviness. The directional metal deposition on 3D structures develops both plasmonic diffraction colors are otherwise difficult to achieve conventional ...

The lung parenchyma provides a maximal surface area of blood-containing capillaries that are in close contact with a large surface area of the air-containing alveoli. Volume and surface area of capillaries are the classic stereological parameters to characterize the alveolar capillary network (ACN) and have provided essential structure-function information of the lung. When loss (rarefaction) o...

microfluidic flow focusing devices have been utilized for droplet generation on account of its superior control over droplet size. droplet based microfluidics addressed many scientific issues by providing a novel technological platform for applications such as biology, pharmaceutical industry, biomedical studies and drug delivery. this study numerically investigated the droplet generation proce...

This paper aims to simulate an immiscible two-phase flow in two-dimensional T-shaped, modified cross-shaped, and cross-shaped micromixers numerically. The effects of various parameters, including Capillary number, phase rate ratio, channel width on the generation droplets were studied. Also, modification T-shaped was proposed. results reveal that equidistant tiny are generated compared ordinary...

the phenomenological model of khossravi and connors (1992) has been adopted to calculate the electrophoretic mobility of drugs at different concentrations of solvents in a binary mixture. the accuracy and predictability of the model have been evaluated employing 14 experimental data sets by using average percentage mean deviation (apmd). the obtained apmd for correlative and predictive studies ...

Individual pulmonary capillaries are not steadily perfused. By using in vivo microscopy, it can readily be demonstrated that perfusion continually switches between capillary segments and between portions of the network within a single alveolar wall. These changes in capillary perfusion occur even when upstream pressure and flow are constant. Flow switching between capillary segments in the abse...