The influence of positioning and geometry of ventricular cannulas for contemporary continuous flow Left Ventricular Assist Devices (LVADs) was evaluated in a non-beating isolated heart preparation with borescopic visualization. Preload and LVAD flow were varied to evaluate degrees of ventricular decompression up to the point of ventricular collapse. The performance of a flanged cannula was comp...

STUDY OBJECTIVE Although preoxygenation for emergency airway management is usually performed with nonrebreather face masks or bag-valve-mask devices, some clinicians also deliver supplemental high-flow oxygen by nasal cannula. We aim to measure the efficacy of supplemental nasal cannula oxygen delivery to conventional bag-valve-mask and nonrebreather face mask preoxygenation both with and witho...

STUDY OBJECTIVES The published AASM guidelines approve use of a nasal cannula/pressure transducer to detect apneas/hypopneas, but require esophageal manometry for Respiratory Effort-Related Arousals (RERAs). However, esophageal manometry may be poorly tolerated by many subjects. We have shown that the shape of the inspiratory flow signal from a nasal cannula identifies flow limitation and eleva...

This paper presents a novel method to predict the occlusion of a withdrawing cannula during extracorporeal circulation due to a networked intensive care setup. During in-vivo experiments we were able to detect the cannula suction up to 90 seconds prior to the collapse of extracorporeal blood flow. The elaborated metric is based on heart rate, extracorporeal blood flow and blood pressure at the ...

The role of nucleus tractus solitarius (NTS) in cardiovascular system regulation is controversial. On the other hand, the problem of hypertension in diabetic animals is the subject of many research programs. The aim of present study was to determine whether inactivation of NTS could affect blood pressure and heart rate in diabetic rats. To this end, stereptozotocin induced diabetic rats were an...

BACKGROUND Peripheral Intravenous cannula (IV) is the most common vascular access device used to administer medications with the exception of medication or fluid with high or low PH or hyperosmolarity which may cause severe damage to small veins. The insertion of a peripheral intravenous cannula in newborn infants can be difficult. Appropriate veins with sufficient capacity to insert a cannula ...

PURPOSE To evaluate MRI issues at 3-Tesla for a ventricular assist device (VAD). METHODS The AB5000 Ventricle with a prototype Nitinol wire-reinforced In-Flow Cannula and Out-Flow Cannula attached (Abiomed, Inc., Danvers, MA) was evaluated for magnetic field interactions, heating, and artifacts at 3-Tesla. MRI-related heating was assessed with the device in a gelled-saline-filled, head/torso ...

BACKGROUND Stroke after open heart surgery is a major cause of morbidity and mortality. Up to 60% of intraoperative cerebral events are caused by emboli generated by manipulations of the aorta during surgery. This is the first animal study evaluating the safety and efficacy of a novel aortic cannula designed to extract solid and gaseous emboli during cardiac surgery. METHODS Seven domestic pi...

AIMS To demonstrate the feasibility and safety of percutaneous delivery of the novel inflow cannula of the CircuLite® SYNERGY® pocket Micro-pump via transseptal access in the swine model. METHODS AND RESULTS After transseptal puncture, the inflow cannula system was advanced into the left atrium (LA) via the right external jugular vein and anchored onto the atrial septum under fluoroscopic and...