Parainfluenza virus type 3 has been isolated from the cerebral spinal fluid (CSF) from six individuals—four children and two adults—over a 10-year period. All had fever, and four had signs of meningitis. All recovered uneventfully, including one child undergoing chemotherapy for medulloblastoma. The clinical presentation of this child who developed parainfluenza virus type 3 meningitis is descr...

Actinomycin D inhibited the yield of influenza virus hemagglutinin from MDCK cells infected at high multiplicity, but had little effect on the yield of parainfluenza virus hemagglutinin. In similar hemagglutinin yield experiments, ribavirin was only slightly more active (threefold) against influenza virus than against parainfluenza virus replication. In plaque inhibition experiments, ribavirin ...

canine distemper virus (cdv) creates a very contagious viral multi-systemic canine distemper (cd) disease that affects most species of carnivora order. the virus is genetically heterogeneous, particularly in section of the hemagglutinin (h) gene. sequence analysis of the h gene can be useful to investigate distinction of various lineages related to geographical distribution and cdv molecular ep...

An association exists between respiratory viruses and bacterial infections. Prevention or treatment of the preceding viral infection is a logical goal for reducing this important cause of morbidity and mortality. The ability of the novel, selective parainfluenza virus hemagglutinin-neuraminidase inhibitor BCX 2798 to prevent the synergism between a paramyxovirus and Streptococcus pneumoniae was...

Parainfluenza virus (PIV) is a leading cause of respiratory infections in humans. A novel virus closely related to human and bovine parainfluenza viruses types 3 (HPIV-3 and BPIV-3), named Tursiops truncatus parainfluenza virus type 1 (TtPIV-1), was isolated from a dolphin with respiratory disease. We developed a dolphin-specific ELISA to measure acute- and convalescent-phase PIV antibodies in ...

BACKGROUND Human Parainfluenza viruses are a common cause of both upper and lower respiratory tract infections, particularly in children. Of the four Parainfluenza virus serotypes, Parainfluenza 4 is least well characterised from both the clinical, epidemiological and genetic perspectives. METHODS Flocked nose or throat swabs from a previous study investigating viral prevalence in community-b...

One of the major agents of infectious tracheobronchitis in dogs is canine parainfluinza virus (CPiV) which is known to cause acute-onset and highly transmissible cough. This study was aimed at determining the prevalence of CPI infection in dogs referred to the Veterinary Clinic of Shiraz University in 2013–2014. Nasal and tracheal swabs were taken from 30 apparently healthy dogs without respira...