Vaccination is time consuming and often labor intensive. This study found that porcine circovirus type 2 vaccination of growing pigs could be performed faster using an intradermal, needle-free method compared to the traditional, intramuscular needle without compromising production parameters antimicrobial treatments.

porcine necrotic ear syndrome (pnes) in pigs has been reported as an increasing health problem in many countries with intensive pig farming. the etiology of this disease is complex and the presumed triggering factors can be divided into infectious and non-infectious agents. the present report describes a case of porcine circovirus type 2 (pcv2), infection associated with lesions of pnes at the ...

The replication proteins Rep and Rep' of porcine circovirus type 1 (PCV1) are both capable of introducing and resealing strand discontinuities at the viral origin of DNA replication in vitro underlying genome amplification by rolling-circle replication. The PCV1 origin of replication encompasses the minimal binding site (MBS) of the Rep and Rep' proteins and an inverted repeat with the potentia...

Porcine circovirus type 1 (PCV1), originally isolated as a contaminant of PK-15 cells, is nonpathogenic, whereas porcine circovirus type 2 (PCV2) causes an economically important disease in pigs. To determine the factors affecting virus replication, we constructed chimeric viruses by swapping open reading frame 1 (ORF1) (rep) or the origin of replication (Ori) between PCV1 and PCV2 and compared...

In October 2016, porcine circovirus type 3 (PCV3) was identified as a pathogen agent for pigs in the United States. Here, we report the genome sequence of a Chinese PCV3 strain, PCV3/CN/Hubei-618/2016. This will help us better understand the epidemiology and genetic characteristics of PCV3.

A novel duck circovirus (DuCV) strain, designated GH01, was isolated from ducklings in southwestern China. We report the genome sequence of GH01 and the genomic organization and genetic relationship to other DuCVs. The availability of the genome sequence will be helpful to investigations of epidemiology and the evolutionary biology of this organism and the development of preventive vaccines.

A plasmid-based transfection system capable of generating infectious porcine circovirus type 2 (PCV2) was established. This system was then used in mutagenesis studies to investigate the involvement of a "conserved" nonanucleotide (which constitutes a portion of the loop sequence) located at the origin of DNA replication of PCV2 with respect to viral protein synthesis, DNA self-replication, and...

In 2010, Rotarix was found to be contaminated with infectious porcine circovirus type 1 (PCV1). In China, the Lanzhou lamb rotavirus (LLR) vaccine is the only vaccine used to prevent rotavirus disease. From 2006 to September 2014, more than 54 million doses of LLR vaccines have been lot released. It is a safety issue whether PCV1 is present in the LLR vaccine. Although the cell substrate of LLR...

The pathogenicity of PCV 2 in the body vaccinated piglets was studied based on results pathomorphological changes lungs and liver animals. work carried out commercial with vaccine Ingelvak CircoFLEX (Germany) against circovirus. used clinical, zootechnical, enzyme immunoassay research methods. It has been established that under conditions ongoing vaccination PCV2, 30.3% still do not have virus-...