Abstract Background: Candidemia is the main cause of fungal nosocomial bloodstream infections and is related to meaningful mortality specially, in pediatrics. Mortality rate range from 5% to 71%, and it can reach as high as 81%. Delays in beginning of treatment have also been linked to intensified mortality. The epidemiology of Candida infection is changing from region to region. Regiona...

background and purpose: by using advanced detection/identification methods, the list of emerging uncommon opportunistic yeast infections is rapidly expanding worldwide. our aim in the present study was sequence-based species delineation of previously unidentified yeasts obtained from a clinically yeast collection. materials and methods: a total of twenty three out of the 855 (5.7%) yeast isolat...

Vulvovaginal candidiasis is caused by the increasing number of Candida species as normal flora in the vagina. To assess the transmission rout as well as to determine the suitable antifungal drugs for treatment, the exact identification of Candida species is crucial. Therefore, earlier detection of infection allows quick initiation of antifungal therapy with a greater probability for improved su...

background candiduria is a rising condition among hospitalized patients and candida albicans is the most common recovered agent. however, non-albicans candida species (nacs) such as c. glabrata, c. krusei, c. parapsilosis, and c. tropicalis are also important. although most candida species especially c. albicans are sensitive to routinely used antifungals, an increasing trend in resistance has ...

Background and Purpose: Treatment of life-threatening fungal infections caused by Candida species has become a major problem. Candida spp. are the most important causative agents of candidiasis. Allium tripedale is a medicinal plant that has been traditionally used to treat infections. In the present study, we aimed to determine the chemical compounds and antimicrobial activity of hydroalcoholi...

Introduction: Increasing rate of candidiasis prevalence and consequently use of antifungal drugs as prophylactic and curative agents has led to the widespread emergence of resistant strains. Therefore this study was designed to evaluate the in vitro antifungal activity of an aqueous extract of garlic and the synergic effect of garlic extract with fluconazole against common clinical isolates of ...

background: due to the predisposing conditions in patients with cystic fibrosis (cf) caused by defective mucociliary clearance facilitating colonization and invasion with candida species has dramatically increased. traditional methods for identifying problems are imminent and time-consuming. therefore, molecular techniques utilizing amplification of target dna provide quick and precise methods ...

Background and Purpose: Candida species are the most common organisms involved in superficial fungal infections, worldwide. Although econazole is among the most frequently used topical formulations for the treatment of candidiasis, no information is available regarding the susceptibility profiles of Candida species in Iran. Materials and Methods: In vitro susceptibility of 100 clinical Candida...