Precision (target) medicine is proposed as a new strategy to identify and develop highly selective drugs against specific targets for the disease more precise tailoring of medicines target populations patients. can be an important approach create novel safer therapeutics (tyrosine kinase inhibitors, tumour monoclonal antibodies) patients with gene mutation, aberrations, or protein over-expressi...

the aim of this study was to investigate the effects of 12 weeks of walking on plasma levels of leptin in postmenopausal women with breast cancer. nineteen postmenopausal women with breast cancer (age: 55.05+2.7 years) who received surgery, chemotherapy and radiation-therapy and were receiving hormone therapy by letrozol were divided into two groups: control (n=8) and experimental (n=11). subje...

colorectal cancer (crc) is the second leading cause of cancer death. progress has been made in the development of chemotherapy for advanced crc. targeted therapies against vegf or egfr are now commonly used. however, many cases show that tolerance develops to such treatments; therefore, new strategies are required to replace or complement current therapies. nuclear factor-?b (nf-?b) transcripti...