cancer of the stomach carries poor prognosis. surgery is the best treatment for gastric cancer. prediction of survival depends on the stage at the time of presentation. fluoroscopy, sonography, and computerized tomography are used for advanced gastric cancers staging, but they are not accurate enough to grade advanced gastric cancers. laparoscopic findings of lesions under direct vision, are ma...

background little is known about the possible influence of demographic and histological risk factors on the survival of patients with esophageal and gastric cancer. objectives based on the available registry and follow-up information, this study compares 1-5 year survival rate of gastric and esophageal cancer. patients and methods through a concurrent (prospective) cohort study, all 366 patient...

inflammatory condition is the consequence of defensive mechanism of immune system against viral and bacterial infection, tissue injury, uv radiation, stress and etc. persistently acute inflammation leads to chronic phase which is characterized by production of pro-inflammatory mediators from t cells. these molecules (e.g. il-6, tnf-α, il-1β and il-17) are mostly pleiotropic cytokines involved i...

background: gastric cancer is an important health problem across the world. chemotherapy in combination with local treatment is standard treatment for locally advanced gastroesophageal cancers. the purpose of this investigation was evaluation of response and tolerability to neoadjuvant eox regimen in locoregionally advanced gastric cancer. materials and methods: patients with locoregionally adv...

background: breast cancer is one of the most common malignancies among iranian women; however, its clinicopathological feature is uncertain. we pioneered a genetic counseling program among patients with breast cancer and their families in isfahan. this is the first report of this program. methods: this was a descriptive cross-sectional study on women with breast cancer registered in ala cancer ...

background: breast and testicular cancers affect a substantial and increasing proportion of the global population. self-examination encourages early detection and treatment of these cancers, which positively impacts on patient quality of life and survival. methods: the present study investigated the role of body esteem in breast and testicular self-examination. men ( n = 60) and women ( n = 90)...

background: proliferation and expansion of cancer stem cells as spheroids were proved in previous studies. but, capability of primary tumor-derived stem cells to keep their unique properties in vitro is still disputed. so, the goal of this study was to isolate, expand and characterize of colon cancer-derived stem cells. material and methods: in the present work, colon cancer stem cells markers ...

rarely, do we think of cancer as “bacterial”, such that we are often told that “cancer is not contagious” persistent bacterial infections cause persistent irritation of the host’s defense systems, which when ineffective in eradication of the infection, result in a multitude of self-destructive damages. this in some cases occurs to such severity that the resulting cellular hyper-proliferation pr...

receptors and proteins are overexpressed in many human cancer cell membranes rather than normal tissues and are considered as the main molecular targets. specific tumor- targeting molecules which have high affinity for these receptors can be valuable tools as carrier molecules for targeted cancer therapy and imaging. pharmacokinetics and bioavailability of diagnostic and therapeutic agents are ...

cancer is uncontrolled and unrestricted growth of malignant cells in the body. it is a multifactorial disease which either heredity or environmental factors (such as nutrition, physical inactivity, alcohol, obesity, exposure to sun, environmental pollutants, infections) contribute to the incidence of cancer. in recent years, several lines of research have focused on obesity as a potent risk fac...