Calcium phosphate ceramics, commonly applied as bone graft substitutes, are a natural choice of scaffolding material for bone tissue engineering. Evidence shows that the chemical composition, macroporosity and microporosity of these ceramics influences their behavior as bone graft substitutes and bone tissue engineering scaffolds but little has been done to optimize these parameters. One method...

Low-voltage-activated (T-type) calcium channels are important regulators of the transmission of nociceptive information in the primary afferent pathway and finding ligands that modulate these channels is a key focus of the drug discovery field. Recently, we characterized a set of novel compounds with mixed cannabinoid receptor/T-type channel blocking activity and examined their analgesic effect...

      The in vitro dissolution of plasma-sprayed hydroxyapatite (PHA) coatings with different characteristics, produced by various spraying conditions, in a Tris-buffered solution at pH 7.4 was experimentally studied through the measurement of calcium ions release with Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES), and then modeled. Three coating characteristics, th...

Phosphorus (P) is one of the primary nutrients generating eutrophication in aquatic systems1. To prevent eutrophication, municipal or agricultural wastewaters are treated to reduce the phosphorus concentrations in the wastewater reaching surface water streams. While unregulated P is a pollutant in a water body, phosphorous is a useful resource in agricultural fertilizers, food supply, and indus...

Response surface methodology (RSM) was used to investigate the preparation-process parameters on calcium acetate from eggshell. Box-Behnken employed for experimental design, and optimal combination of reaction temperature, solid-liquid ratio, acetic acid concentration, primary time secondary preparing analyzed. Multiple regression analysis fit data second-order polynomial equation, appropriate ...

We describe a unified formulation and algorithm to find an extremely sparse representation for Calcium image sequences in terms of cell locations, cell shapes, spike timings and impulse responses. Solution of a single optimization problem yields cell segmentations and activity estimates that are on par with the state of the art, without the need for heuristic preor postprocessing. Experiments o...