BACKGROUND The Canadian Health Measures Survey (CHMS) is an ongoing cross-sectional national survey that includes a measure of 25-hydroxyvitamin D [25(OH)D] by immunoassay. For cycles 1 and 2, the collection period occurred approximately every 2 y, with a new sample of ∼5600 individuals. OBJECTIVE The goal was to standardize the original 25(OH)D CHMS values in cycles 1 and 2 to the internatio...

The original version of this Article contained a typographical error in the spelling of the author Sandra Maria Matta which was incorrectly given as Sandra da Matta. This has now been corrected in both the PDF and HTML versions of the Article. In addition, there was a typographical error in the spelling of the author Tatiane Assone which was incorrectly given as Tatiane Assone Assone in the HTM...

BACKGROUND Low serum levels of 25-hydroxyvitamin D [25(OH)D] have been associated with a high risk of breast cancer. Since publication of the most current meta-analysis of 25(OH)D and breast cancer risk, two new nested case-control studies have emerged. MATERIALS AND METHODS A PubMed search for all case-control studies on risk of breast cancer by 25(OH)D concentration identified 11 eligible s...

The metabolism of vitamin D(3) has been studied after intravenous injection of 10 IU of [1,2-(3)H]-vitamin D(3) to vitamin D-deficient rats. The disappearance of the radioactivity from the plasma follows a very peculiar pattern characterized by an early rapid disappearance followed by a rebound of radioactivity before assuming still a third rather slow disappearance rate. The "rebound" phenomen...

Scientists and physicians have suggested that poor vitamin D intake can result in increased cardio-vascular mortality. Also total mortality appears to be increased with poor vitamin D status. A research team of the German Cancer Research Center in Heidelberg (DKFZ) headed by Ben Schöttker was able to demonstrate this association in a meta-analysis of 8 European and US-based cohort studies. In a...

The objective of this study is to examine and evaluate whether serum 25(OH)D is associated with disease activity in patients with rheumatoid arthritis (RA). Our results suggested that serum 25(OH)D in RA groups has significant lower level (35.99 ± 12.59 nmol/L) than that in the normal groups (54.35 ± 8.20 nmol/L, P < 0.05). Based on the DAS28, patients with RA were divided into four subgroups, ...