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Acute kidney injury (AKI) is a frequent and critical complication in the clinical setting. In rodents, AKI can be effectively prevented through caloric restriction (CR), which has also been shown to increase lifespan many species. Caenorhabditis elegans (C. elegans), longevity studies revealed that marked CR-induced reduction of endocannabinoids may key mechanism. Thus, we hypothesized regulati...

Background: The genus Caenorhabditis has been central to our understanding of metazoan biology. The best-known species, Caenorhabditis elegans, is but one member of a genus with around 50 known species, and knowledge of these species will place the singular example of C. elegans in a rich phylogenetic context. How did the model come to be as it is today, and what are the dynamics of change in t...

In traditional medicine, Jasonia glutinosa (L.) DC or rock tea (RT) has been mainly used to treat digestive and respiratory pathologies but also as an antimicrobial antidepressant herbal remedy. An ethanolic extract of RT demonstrated have antioxidant anti-inflammatory effects, which may be explained by its phytochemical profile, rich in polyphenols pigments. The aim this study is investigate t...